Mariri
Banisteriopsis caapi
Banisteriopsis caapi is a South American vine traditionally used in the preparation of ayahuasca, an important component in traditional medicine practices among indigenous communities in the Amazon basin. While its specific uses are not well-documented, it is known for being a key ingredient in ayahuasca brews, which are often used in spiritual and healing ceremonies. Scientific evidence suggests potential therapeutic benefits from compounds found in B. caapi, particularly DMT (dimethyltryptamine) and 5-MeO-DMT, with some studies indicating possible efficacy for treatment-resistant depression and major depressive disorder; however, more clinical trials are needed to confirm these findings. Additionally, β-carbolines present in the plant have shown potential anti-inflammatory and neuroprotective effects, as evidenced by their ability to reduce cytokine production in cell cultures. No significant safety concerns or drug interactions have been recorded for B. caapi, though further research is necessary to fully understand its long-term effects and interactions with other substances.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The blood sample of the patient contained DMT and other β-carbolines commonly found in ayahuasca, along with other drugs.
- Machine learning algorithms achieved up to 90% accuracy in classifying Banisteriopsis caapi folk types using leaf images.
- Current evidence suggests potential therapeutic benefits of DMT and 5-MeO-DMT for treatment-resistant depression and major depressive disorder, though more clinical trials are needed.
- β-carbolines and B. caapi extract reduced LPS-induced cytokine production in SH-SY5Y cells, potentially offering anti-inflammatory and neuroprotective benefits.
Frequently asked questions
What is Mariri?
Mariri (Banisteriopsis caapi) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Mariri?
4 sourced findings are recorded for Mariri; the strongest carries evidence grade D. For example: The blood sample of the patient contained DMT and other β-carbolines commonly found in ayahuasca, along with other drugs.
How strong is the evidence for Mariri?
The strongest finding for Mariri carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Mariri safe? What are the side effects?
No major safety issues are recorded for Mariri in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Mariri interact with medications?
No drug interactions are recorded for Mariri in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Mariri?
Mariri is also known as: Лоза духов.
Is Mariri a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Intoxication Associated with Ayahuasca Consumption, Characterization, and Comparative Analysis of the Beverage's Components: A Case Report. literature abstract metadata
- T2 Anti-inflammatory effects of Banisteriopsis caapi and beta-carbolines in neuronal cells: potential implications for neuro-COVID. literature abstract metadata
- T2 Ayahuasca and Its Main Component N,N-Dimethyltryptamine (DMT) for the Treatment of Mental Disorders: Mechanisms of Action, Clinical Studies, and Tools to Explore the Human Mind. literature abstract metadata
- T2 Machine learning recovers folk classification of Banisteriopsis caapi from herbarium leaves an ayahuasca liana. literature abstract metadata