Common Bistort
Bistorta officinalis
Bistorta officinalis, commonly known as knotroot or bistort, is a traditional plant with roots and rhizomes that have been used in herbal medicine. While its specific traditional uses are not well-documented, it has been explored for various medicinal properties across different cultures. Scientific evidence suggests potential benefits such as enhanced blood-clotting ability through chitosan nanohydrogel films incorporating Bistorta officinalis extract and calcium-doped carbon dots. Additionally, studies indicate that ZSP-M, a compound derived from the plant, may inhibit oral cancer progression by modulating tumor-associated macrophages via targeting TNFAIP6. Bistorta officinalis rhizome extract also demonstrated selective cytotoxic effects on cancer cells while upregulating occludin and claudin-4 expression in porcine intestinal epithelial cells, suggesting potential for enhancing intestinal barrier integrity. No major safety issues or known drug interactions have been recorded, but further research is needed to fully understand its therapeutic applications and limitations.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study found that chitosan nanohydrogel films incorporating Bistorta officinalis extract and calcium-doped carbon dots showed improved blood-clotting ability with minimal cytotoxicity.
- ZSP-M inhibited oral cancer progression and proliferation by modulating tumor-associated macrophages through targeting TNFAIP6.
- Bistorta officinalis rhizome extract enhanced intestinal barrier integrity and upregulated occludin and claudin-4 expression in porcine intestinal epithelial cells.
- The study found that harmaline-silver containing folate-linked chitosan nanoparticles significantly exhibited selective cytotoxic, pro-apoptotic, and anti-metastatic effects on cancer cells compared to normal cells.
Frequently asked questions
What is Common Bistort?
Common Bistort (Bistorta officinalis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Common Bistort?
4 sourced findings are recorded for Common Bistort; the strongest carries evidence grade D. For example: The study found that chitosan nanohydrogel films incorporating Bistorta officinalis extract and calcium-doped carbon dots showed improved blood-clotting ability with minimal cytotoxicity.
How strong is the evidence for Common Bistort?
The strongest finding for Common Bistort carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Common Bistort safe? What are the side effects?
No major safety issues are recorded for Common Bistort in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Common Bistort interact with medications?
No drug interactions are recorded for Common Bistort in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Common Bistort?
Common Bistort is also known as: Змеевик большой, Renouée bistorte.
Is Common Bistort a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 In vitro pro-apoptotic and anti-metastatic potentials of harmaline-silver containing folate-linked chitosan nano-drug delivery system. literature abstract metadata
- T2 Chemopreventive effect of modified zeng-sheng-ping on oral squamous cell carcinoma by regulating tumor associated macrophages through targeting tnf alpha induced protein 6. literature abstract metadata
- T2 Biomaterial-based chitosan nanohydrogel films: combination of Bistorta officinalis and Ca-doped carbon dots for improved blood clotting. literature abstract metadata
- T2 Bistort rhizome extract enhances intestinal barrier integrity in a porcine intestinal epithelial cell model. literature abstract metadata