Common Bistort

Bistorta officinalis

Bistorta officinalis, also known as Bistort, is a traditional plant used in various herbal practices. While its specific uses are not well-documented in historical traditions, it has shown promise in modern scientific research. Studies have indicated that extracts from the rhizome of Bistorta officinalis may enhance intestinal barrier integrity and modulate tumor-associated macrophages, potentially impacting cancer progression. Additionally, chitosan nanohydrogel films incorporating Bistorta officinalis extract showed improved blood-clotting ability with minimal cytotoxicity. Harmaline-silver containing folate-linked chitosan nanoparticles derived from this plant exhibited selective cytotoxic and anti-metastatic effects on cancer cells. To date, no major safety issues or drug interactions have been recorded for Bistorta officinalis, but further research is needed to fully understand its potential applications and implications.

At a glance
Best evidence
D
Cautions

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • The study found that chitosan nanohydrogel films incorporating Bistorta officinalis extract and calcium-doped carbon dots showed improved blood-clotting ability with minimal cytotoxicity. D PMID
  • ZSP-M inhibited oral cancer progression and proliferation by modulating tumor-associated macrophages through targeting TNFAIP6. D PMID
  • Bistorta officinalis rhizome extract enhanced intestinal barrier integrity and upregulated occludin and claudin-4 expression in porcine intestinal epithelial cells. D PMID
  • The study found that harmaline-silver containing folate-linked chitosan nanoparticles significantly exhibited selective cytotoxic, pro-apoptotic, and anti-metastatic effects on cancer cells compared to normal cells. D PMID

Frequently asked questions

What is Common Bistort?

Common Bistort (Bistorta officinalis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Common Bistort?

4 sourced findings are recorded for Common Bistort; the strongest carries evidence grade D. For example: The study found that chitosan nanohydrogel films incorporating Bistorta officinalis extract and calcium-doped carbon dots showed improved blood-clotting ability with minimal cytotoxicity.

How strong is the evidence for Common Bistort?

The strongest finding for Common Bistort carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Common Bistort safe? What are the side effects?

No major safety issues are recorded for Common Bistort in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Common Bistort interact with medications?

No drug interactions are recorded for Common Bistort in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Common Bistort?

Common Bistort is also known as: Змеевик большой, Renouée bistorte.

Is Common Bistort a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 In vitro pro-apoptotic and anti-metastatic potentials of harmaline-silver containing folate-linked chitosan nano-drug delivery system. literature abstract metadata
  2. T2 Chemopreventive effect of modified zeng-sheng-ping on oral squamous cell carcinoma by regulating tumor associated macrophages through targeting tnf alpha induced protein 6. literature abstract metadata
  3. T2 Biomaterial-based chitosan nanohydrogel films: combination of Bistorta officinalis and Ca-doped carbon dots for improved blood clotting. literature abstract metadata
  4. T2 Bistort rhizome extract enhances intestinal barrier integrity in a porcine intestinal epithelial cell model. literature abstract metadata