Bridelia retusa
Bridelia retusa
Bridelia retusa is a plant traditionally used in various folk medicine practices, particularly in Southeast Asia. While its specific traditional uses are not well-documented, it has been explored for potential medicinal properties. Scientific evidence suggests that compounds from Bridelia retusa, such as ellagic acid and (+)-sesamin, may have potential against SARS-CoV-2 3CL pro through in silico studies. Additionally, silver nanoparticles synthesized from its leaf extracts showed promising anti-biofilm activity against certain human pathogens. In animal models, bark extracts demonstrated significant analgesic, anti-inflammatory, and anti-arthritic effects. However, the evidence for these properties is still preliminary and more research is needed to confirm their efficacy. No major safety concerns or known drug interactions have been recorded for Bridelia retusa; however, further studies are required to fully understand its potential benefits and risks.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study identified ellagic acid and (+)-sesamin from Bridelia retusa as potential inhibitors of SARS-CoV-2 3CL pro through in silico techniques.
- The study found that silver nanoparticles synthesized from Bridelia retusa leaf extracts showed potential anti-biofilm activity against certain human pathogens.
- Bridelia retusa bark extracts showed significant analgesic, anti-inflammatory, and anti-arthritic activity in animal models.
- The study found that pinocembrin-7-O-β-D-glucopyranoside from Acacia pennata had the most stable complex with β-lactamase, potentially inhibiting it to combat antibiotic resistance.
Frequently asked questions
What is Bridelia retusa?
Bridelia retusa (Bridelia retusa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Bridelia retusa?
4 sourced findings are recorded for Bridelia retusa; the strongest carries evidence grade D. For example: The study identified ellagic acid and (+)-sesamin from Bridelia retusa as potential inhibitors of SARS-CoV-2 3CL pro through in silico techniques.
How strong is the evidence for Bridelia retusa?
The strongest finding for Bridelia retusa carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Bridelia retusa safe? What are the side effects?
No major safety issues are recorded for Bridelia retusa in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Bridelia retusa interact with medications?
No drug interactions are recorded for Bridelia retusa in our sources. This does not rule them out — check with a pharmacist.
Is Bridelia retusa a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Evaluation of analgesic and anti-inflammatory activity of Bridelia retusa (Spreng) bark. literature abstract metadata
- T2 Anti-biofilm and Antibacterial Activities of Silver Nanoparticles Synthesized by the Reducing Activity of Phytoconstituents Present in the Indian Medicinal Plants. literature abstract metadata
- T2 Antiviral phytocompounds "ellagic acid" and "(+)-sesamin" of Bridelia retusa identified as potential inhibitors of SARS-CoV-2 3CL pro using extensive molecular docking, molecular dynamics simulation studies, binding free energy calculations literature abstract metadata
- T2 In-silico screening of Acacia pennata and Bridelia retusa reveals pinocembrin-7-O-β-D-glucopyranoside as a promising β-lactamase inhibitor to combat antibiotic resistance. literature abstract metadata