Callicarpa nudiflora
Callicarpa nudiflora
Callicarpa nudiflora is a plant traditionally used in East Asian medicine but lacks specific documented traditional uses. Scientific evidence suggests potential benefits, such as enhanced anti-inflammatory and antioxidant effects, particularly in colitis models. It also shows promise in improving small intestinal injury by modulating gut microbiota and inhibiting inflammatory signaling pathways. Additionally, supplementation with a polyherbal mixture including Callicarpa nudiflora has been associated with a significant decrease in calf diarrhea incidence. Eight diterpenoids have been isolated from the plant, some of which exhibit certain anti-inflammatory activity. No major safety issues or drug interactions have been recorded to date.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- CN-EVLP-Bud showed enhanced anti-inflammatory and antioxidant effects compared to free budesonide in colitis models.
- Supplementation with a polyherbal mixture including Callicarpa nudiflora significantly decreased calf diarrhea incidence.
- CNLP improved LPS-induced small intestinal injury by modulating gut microbiota and inhibiting inflammatory signaling.
- Eight diterpenoids were isolated from Callicarpa nudiflora, with compounds 1 and 5 showing certain anti-inflammatory activity.
Frequently asked questions
What is Callicarpa nudiflora?
Callicarpa nudiflora (Callicarpa nudiflora) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Callicarpa nudiflora?
4 sourced findings are recorded for Callicarpa nudiflora; the strongest carries evidence grade D. For example: CN-EVLP-Bud showed enhanced anti-inflammatory and antioxidant effects compared to free budesonide in colitis models.
How strong is the evidence for Callicarpa nudiflora?
The strongest finding for Callicarpa nudiflora carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Callicarpa nudiflora safe? What are the side effects?
No major safety issues are recorded for Callicarpa nudiflora in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Callicarpa nudiflora interact with medications?
No drug interactions are recorded for Callicarpa nudiflora in our sources. This does not rule them out — check with a pharmacist.
Is Callicarpa nudiflora a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Callicarpa nudiflora Hook polysaccharides improve lipopolysaccharide-induced small intestinal injury by modulating gut microbiota metabolism and inhibiting NF-κB/MAPK signaling. literature abstract metadata
- T2 [Diterpenoids from leaves of Callicarpa nudiflora and their anti-inflammatory activities]. literature abstract metadata
- T2 Callicarpa nudiflora-derived extracellular vesicle-like particles loaded with budesonide enhance the treatment of ulcerative colitis by regulating M1/M2 macrophage polarization. literature abstract metadata
- T2 Mechanism of a polyherbal mixture alleviates calf diarrhea: an integrated network pharmacology, metabolomics, and microbiome study. literature abstract metadata