Catharanthus trichophyllus
Catharanthus trichophyllus
Catharanthus trichophyllus is a plant traditionally used in certain herbal practices but lacks specific documented traditional uses. Scientific research has identified several bioactive compounds, including nine alkaloids from its roots and 39 compounds from its leaves, some of which show potential analgesic, thrombolytic, and membrane-stabilizing activities. Studies have shown that UA-NPs (unspecified active substances nanoparticles) more effectively inhibited liver cancer cell growth and tumor development compared to free UA, while transformed Catharanthus trichophyllus roots are 100 to 1000 times more sensitive to auxin than normal roots. The isolation of cathaphylline from the roots and the identification of various compounds in the leaves suggest potential therapeutic applications, though current scientific evidence is limited. No major safety issues or drug interactions have been recorded for this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- UA-NPs more effectively inhibited liver cancer cell growth and tumor development compared to free UA.
- Catharanthus trichophyllus roots transformed by certain DNA from Agrobacterium are 100 to 1000 times more sensitive to auxin than normal roots.
- The study isolated nine alkaloids from Catharanthus trichophyllus roots and described the structure of a new one called cathaphylline.
- A total of 39 compounds were identified from Catharanthus ovalis leaves, with some showing potential analgesic, thrombolytic, and membrane-stabilizing activities.
Frequently asked questions
What is Catharanthus trichophyllus?
Catharanthus trichophyllus (Catharanthus trichophyllus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Catharanthus trichophyllus?
4 sourced findings are recorded for Catharanthus trichophyllus; the strongest carries evidence grade D. For example: UA-NPs more effectively inhibited liver cancer cell growth and tumor development compared to free UA.
How strong is the evidence for Catharanthus trichophyllus?
The strongest finding for Catharanthus trichophyllus carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Catharanthus trichophyllus safe? What are the side effects?
No major safety issues are recorded for Catharanthus trichophyllus in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Catharanthus trichophyllus interact with medications?
No drug interactions are recorded for Catharanthus trichophyllus in our sources. This does not rule them out — check with a pharmacist.
Is Catharanthus trichophyllus a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Catharanthus alkaloids XXXII: isolation of alkaloids from Catharanthus trichophyllus roots and structure elucidation of cathaphylline. literature abstract metadata
- T2 High Sensitivity to Auxin is a Common Feature of Hairy Root. literature abstract metadata
- T2 Efficient delivery of ursolic acid by poly(N-vinylpyrrolidone)-block-poly (ε-caprolactone) nanoparticles for inhibiting the growth of hepatocellular carcinoma in vitro and in vivo. literature abstract metadata
- T2 Chemico-pharmacological evaluation of the methanolic leaf extract of Catharanthus ovalis: GC-MS/MS, in vivo, in vitro, and in silico approaches. literature abstract metadata