Cerbera odollam
Cerbera odollam
Cerbera odollam is a plant native to Southeast Asia, particularly in coastal areas of India. Traditionally, it has not been extensively used in any known medical practices or remedies. However, recent studies have shown potential for its use in biotechnology and medicine. Mathematical models were developed to predict the production of polyhydroxyalkanoate from Cerbera odollam oil by Pseudomonas resinovorans DSM 21078, indicating possible applications in bioengineering. Additionally, research has demonstrated that combining sub-IC50 concentrations of Cerbera odollam fruit fractions with sorafenib significantly enhanced anti-cancer effects in certain cell lines. Notably, the ingestion of Cerbera odollam seeds can lead to severe arrhythmias and electrolyte disturbances, highlighting its potential lethality. To date, no major safety issues or drug interactions have been recorded, but caution is advised due to its known toxicity.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study developed a method for detecting cardiac glycosides from Cerbera odollam in human blood serum and applied it to an actual poisoning case.
- Combining sub-IC50 concentrations of Cerbera odollam fruit fractions with sorafenib significantly enhanced anti-cancer effects in HCT116 and HepG2 cells.
- Two mathematical models were developed to predict polyhydroxyalkanoate production from Cerbera odollam oil by Pseudomonas resinovorans DSM 21078.
- The patient's ingestion of Cerbera odollam seeds led to severe arrhythmias and electrolyte disturbances, highlighting its potential lethality.
Frequently asked questions
What is Cerbera odollam?
Cerbera odollam (Cerbera odollam) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Cerbera odollam?
4 sourced findings are recorded for Cerbera odollam; the strongest carries evidence grade D. For example: The study developed a method for detecting cardiac glycosides from Cerbera odollam in human blood serum and applied it to an actual poisoning case.
How strong is the evidence for Cerbera odollam?
The strongest finding for Cerbera odollam carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Cerbera odollam safe? What are the side effects?
No major safety issues are recorded for Cerbera odollam in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Cerbera odollam interact with medications?
No drug interactions are recorded for Cerbera odollam in our sources. This does not rule them out — check with a pharmacist.
Is Cerbera odollam a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Cerbera odollam fruit extracts enhance anti-cancer activity of sorafenib in HCT116 and HepG2 cells. literature abstract metadata
- T2 Development of an LC-MS/MS detection method for cardiac glycosides (cerberin, neriifolin, and tanghinin) in human blood serum: Application to a Cerbera odollam poisoning case. literature abstract metadata
- T2 Modeling of fermentative polyhydroxyalkanoate production from Cerbera odollam oil using Monod-based and multi-scale kinetic models. literature abstract metadata
- T2 Attempted Suicide by Cerbera odollam Ingestion in Switzerland: A Case Report. literature abstract metadata