Chloranthus henryi
Chloranthus henryi
Chloranthus henryi is a plant traditionally used with no recorded practices in any known medical traditions. Scientific evidence suggests that compounds 8, 10, and 11 from its roots exhibit potent neuroprotective activity against H2O2-induced PC12 cell damage at 10 μM, while other isolated compounds show medium inhibitory activity on nitric oxide generation and anti-inflammatory effects by blocking Akt phosphorylation. Eleven new amides were identified in Chloranthus henryi var. hupehensis, with some showing potential to inhibit inflammatory responses through the IKBα/NF-κB p65 signaling pathway. However, there is currently no recorded safety information indicating major issues or drug interactions associated with this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Compounds 8, 10, and 11 showed potent neuroprotective activity against H2O2-induced PC12 cell damage at 10 μM.
- The study identified new sesquiterpenoids from Chloranthus henryi roots that showed anti-inflammatory activity by suppressing the IKBα/NF-κB p65 signaling pathway.
- Ten compounds, including five new ones, were isolated from Chloranthus henryi, and their structures were determined; some showed medium inhibitory activity on nitric oxide generation.
- The study identified eleven new amides from Chloranthus henryi var. hupehensis and found that certain compounds inhibited inflammatory responses by blocking Akt phosphorylation.
Frequently asked questions
What is Chloranthus henryi?
Chloranthus henryi (Chloranthus henryi) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Chloranthus henryi?
4 sourced findings are recorded for Chloranthus henryi; the strongest carries evidence grade D. For example: Compounds 8, 10, and 11 showed potent neuroprotective activity against H2O2-induced PC12 cell damage at 10 μM.
How strong is the evidence for Chloranthus henryi?
The strongest finding for Chloranthus henryi carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Chloranthus henryi safe? What are the side effects?
No major safety issues are recorded for Chloranthus henryi in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Chloranthus henryi interact with medications?
No drug interactions are recorded for Chloranthus henryi in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Chloranthus henryi?
Chloranthus henryi is also known as: Хлорант Генри.
Is Chloranthus henryi a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Structurally diverse amides from Chloranthus henryi var. hupehensis and their anti-inflammatory activities by blocking Akt phosphorylation. literature abstract metadata
- T2 Isolation and biomimetic synthesis of phenylpropionyl phenylethylamines from Chloranthus henryi. literature abstract metadata
- T2 Discovery of sesquiterpenoids from the roots of Chloranthus henryi Hemsl. var. hupehensis (Pamp.) K. F. Wu and their anti-inflammatory activity by IKBα/NF-κB p65 signaling pathway suppression. literature abstract metadata
- T2 Structurally diversified sesquiterpenoids from Chloranthus henryi and their neuroprotective activities on H2O2 damaged PC12 cells. literature abstract metadata