Ussuri thistle

Cirsium japonicum var. maackii

Cirsium japonicum var. maackii, a plant native to East Asia, has not been traditionally used for medicinal purposes in any known records. In recent scientific studies, MS-10®, which contains components from this plant, showed promise in improving menopausal symptoms and quality of life in premenopausal women; however, the specific contributions of Cirsium japonicum var. maackii to these effects are not clearly defined. Additionally, extracts from Cirsium japonicum var. maackii demonstrated positive outcomes in reducing body weight, fat mass, blood glucose levels, and dyslipidemia in db/db mice, suggesting potential benefits for metabolic health. The ethyl acetate fraction of FCJM (Fukushoken Jikko-Makibisho) also exhibited protective effects against oxidative stress and inflammation induced by Aβ25-35 in C6 glial cells, indicating possible neuroprotective properties. No major safety concerns or recorded drug interactions have been identified for this plant, but further research is necessary to fully understand its potential benefits and mechanisms of action.

At a glance
Best evidence
B
Cautions

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • The study found that sulfoxaflor residues differ between Cirsium japonicum var. maackii and Olea europaea, with varying metabolic pathways and risk levels. D PMID
  • MS-10® improved menopausal symptoms and quality of life by about 48% and 36%, respectively, in premenopausal women. B PMID
  • FCJM, particularly its ethyl acetate fraction, showed protective effects against Aβ25-35-induced oxidative stress and inflammation in C6 glial cells. D PMID
  • Cirsium japonicum var. maackii extract improved insulin resistance, lipid profiles, and reduced liver and kidney damage in type 2 diabetes mouse models. D PMID

Frequently asked questions

What is Ussuri thistle?

Ussuri thistle (Cirsium japonicum var. maackii) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Ussuri thistle?

4 sourced findings are recorded for Ussuri thistle; the strongest carries evidence grade B. For example: The study found that sulfoxaflor residues differ between Cirsium japonicum var. maackii and Olea europaea, with varying metabolic pathways and risk levels.

How strong is the evidence for Ussuri thistle?

The strongest finding for Ussuri thistle carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).

Is Ussuri thistle safe? What are the side effects?

No major safety issues are recorded for Ussuri thistle in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Ussuri thistle interact with medications?

No drug interactions are recorded for Ussuri thistle in our sources. This does not rule them out — check with a pharmacist.

Is Ussuri thistle a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 A Complex of Cirsium japonicum var. maackii (Maxim.) Matisum. and Thymus vulgaris L. Improves Menopausal Symptoms and Supports Healthy Aging in Women. literature abstract metadata
  2. T2 Protective Effects of Cirsium japonicum var. maackii Flower on Amyloid Beta25-35-Treated C6 Glial Cells. literature abstract metadata
  3. T2 Effects of Cirsium japonicum var. maackii on avelliation of metabolic disease by improving insulin resistance. literature abstract metadata
  4. T2 Residue dynamics and metabolic pathways of sulfoxaflor in Cirsium japonicum var. maackii and Olea europaea L. literature abstract metadata