Clematis terniflora var. mandshurica

Clematis terniflora var. mandshurica, also known as Clematis manshurica, is a traditional plant used in East Asian medicine, particularly in Chinese herbalism. It has been traditionally employed for various purposes, though specific uses are not well-documented in the literature. Scientific studies have shown that compounds from its roots and rhizomes exhibit varying inhibitory effects on TNF-α-induced cell proliferation, suggesting potential anti-inflammatory activity. Additionally, a JOINS tablet containing extracts from Clematis manshurica was found to show a greater reduction in low back pain compared to the control group after 6 months of use. Research has also identified nine new oleanane-type triterpenoid saponins with strong anti-inflammatory properties by inhibiting NF-κB activation, further supporting its potential medicinal uses. Notably, SKCPT (a formulation containing Clematis manshurica) was found to be non-inferior to celecoxib in treating knee osteoarthritis and had a similar safety profile. No major safety issues or drug interactions have been recorded for this plant, though further research is warranted to fully understand its therapeutic potential and safety profile.

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.