Pilose bellflower
Codonopsis pilosula
Codonopsis pilosula, a traditional Chinese medicinal plant, is primarily used in East Asian herbal practices. While its specific uses are not well-documented, it has been studied for its potential health benefits. Scientific evidence suggests that microscopic examination and HPLC-UV analysis can effectively authenticate Codonopsis species and detect adulterants. Additionally, supplementation with CGe (a component of Codonopsis pilosula) showed improved growth performance and antioxidant capacity in weaned piglets, though the exact mechanisms are not fully understood. In another study, Codonopsis pilosula polysaccharides from Shenling Baizhu Formula were found to ameliorate ulcerative colitis by activating AMPK-mediated mitophagy and inhibiting the cGAS-STING inflammatory axis. Moreover, ONSMP (another component of Codonopsis) improved cardiac function and reduced myocardial injury in rats with post-myocardial infarction heart failure through activation of the cGMP-PKG-GPX4 axis. No major safety issues or recorded drug interactions have been noted for this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- CGe supplementation showed improved growth performance and antioxidant capacity in weaned piglets without specifying exact mechanisms or doses.
- Microscopic examination combined with HPLC-UV analysis effectively authenticated Panax species and detected common adulterants like Codonopsis pilosula.
- ONSMP improved cardiac function and reduced myocardial injury in rats with PMI-HF by activating the cGMP-PKG-GPX4 axis and suppressing ferroptosis.
- Codonopsis pilosula polysaccharides from Shenling Baizhu Formula ameliorate dextran sulfate sodium-induced ulcerative colitis by activating AMPK-mediated mitophagy to suppress the cGAS-STING inflammatory axis.
Frequently asked questions
What is Pilose bellflower?
Pilose bellflower (Codonopsis pilosula) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Pilose bellflower?
4 sourced findings are recorded for Pilose bellflower; the strongest carries evidence grade D. For example: CGe supplementation showed improved growth performance and antioxidant capacity in weaned piglets without specifying exact mechanisms or doses.
How strong is the evidence for Pilose bellflower?
The strongest finding for Pilose bellflower carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Pilose bellflower safe? What are the side effects?
No major safety issues are recorded for Pilose bellflower in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Pilose bellflower interact with medications?
No drug interactions are recorded for Pilose bellflower in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Pilose bellflower?
Pilose bellflower is also known as: Колокольник мелковолосистый.
Is Pilose bellflower a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Yiqi Huoxue Lishui-based Optimized New Shengmai Powder ameliorates myocardial injury in rats with post-myocardial infarction heart failure by inhibiting oxidative stress-mediated ferroptosis via the cyclic guanosine monophosphate-protein ki literature abstract metadata
- T2 Codonopsis pilosula as the sovereign herb in Shenling Baizhu formula ameliorates DSS-induced ulcerative colitis via spermidine-AMPK-mediated mitophagy to inhibit the cGAS-STING inflammatory axis. literature abstract metadata
- T2 Mechanism of liquiritin from Codonopsis pilosula-Glycyrrhiza uralensis extract in alleviating piglet weaning stress via binding to alpha-1-microglobulin/bikunin precursor by machine learning and molecular dynamics simulation. literature abstract metadata
- T2 Microscopy Combined with LC-UV Analysis as a Tool for Authentication of Ginseng Species Used in Traditional Medicine and Detection of Their Adulterants. literature abstract metadata