Pilose bellflower

Codonopsis pilosula

Codonopsis pilosula is a plant rooted in traditional Chinese medicine. It is historically utilized to address various conditions including anemia, fatigue, spleen and stomach complaints, asthma, and insomnia. Scientific evidence is currently limited and varied; some studies suggest its polysaccharides may ameliorate ulcerative colitis in models, while other research indicates potential benefits for cardiac function and growth performance in piglets. However, much of this data is based on animal models or specific formulas rather than human clinical trials. No major safety issues or notable drug interactions are currently recorded in the available literature.

At a glance
Traditionally for
amnesia · anemia
Traditions
TCM
Best evidence
D
Cautions
—

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

Traditional use

What the science says

  • CGe supplementation showed improved growth performance and antioxidant capacity in weaned piglets without specifying exact mechanisms or doses. D PMID
  • Microscopic examination combined with HPLC-UV analysis effectively authenticated Panax species and detected common adulterants like Codonopsis pilosula. D PMID
  • ONSMP improved cardiac function and reduced myocardial injury in rats with PMI-HF by activating the cGMP-PKG-GPX4 axis and suppressing ferroptosis. D PMID
  • Codonopsis pilosula polysaccharides from Shenling Baizhu Formula ameliorate dextran sulfate sodium-induced ulcerative colitis by activating AMPK-mediated mitophagy to suppress the cGAS-STING inflammatory axis. D PMID

Frequently asked questions

What is Pilose bellflower?

Pilose bellflower (Codonopsis pilosula) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What is Pilose bellflower traditionally used for?

Traditional sources record Pilose bellflower for: amnesia, anemia, anorexia, aperitif, asthma, debility. This reflects traditional use, not a proven medical treatment.

Which traditions use Pilose bellflower?

Pilose bellflower appears in these traditions in our sources: TCM.

What does the scientific evidence say about Pilose bellflower?

4 sourced findings are recorded for Pilose bellflower; the strongest carries evidence grade D. For example: CGe supplementation showed improved growth performance and antioxidant capacity in weaned piglets without specifying exact mechanisms or doses.

How strong is the evidence for Pilose bellflower?

The strongest finding for Pilose bellflower carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Pilose bellflower safe? What are the side effects?

No major safety issues are recorded for Pilose bellflower in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Pilose bellflower interact with medications?

No drug interactions are recorded for Pilose bellflower in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Pilose bellflower?

Pilose bellflower is also known as: Колокольник мелковолосистый.

Is Pilose bellflower a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T3 Dr. Duke's Ethnobotanical Database public domain (USDA ARS — attribute Dr. Duke's)
  2. T2 Yiqi Huoxue Lishui-based Optimized New Shengmai Powder ameliorates myocardial injury in rats with post-myocardial infarction heart failure by inhibiting oxidative stress-mediated ferroptosis via the cyclic guanosine monophosphate-protein ki literature abstract metadata
  3. T2 Codonopsis pilosula as the sovereign herb in Shenling Baizhu formula ameliorates DSS-induced ulcerative colitis via spermidine-AMPK-mediated mitophagy to inhibit the cGAS-STING inflammatory axis. literature abstract metadata
  4. T2 Mechanism of liquiritin from Codonopsis pilosula-Glycyrrhiza uralensis extract in alleviating piglet weaning stress via binding to alpha-1-microglobulin/bikunin precursor by machine learning and molecular dynamics simulation. literature abstract metadata
  5. T2 Microscopy Combined with LC-UV Analysis as a Tool for Authentication of Ginseng Species Used in Traditional Medicine and Detection of Their Adulterants. literature abstract metadata