FolkKB

Marsh Cinquefoil

Comarum palustre

Comarum palustre, commonly known as bog cotton or marsh rosemary, is a traditional plant found in wetland environments. While its use in traditional medicine has not been extensively documented, studies have shown potential benefits for individuals with osteoarthritis and diabetes mellitus (DM). Research indicates that Comarum palustre may contribute to pain reduction, improvement in symptoms and disability associated with knee osteoarthritis, as well as changes in cholesterol levels and cytokine concentrations. The plant's genome has been sequenced, revealing 37,459 protein-coding genes and providing insights into its metabolic adaptations, particularly in response to hypoxic conditions. Rheological properties of Ca-gels derived from Comarum palustre pectin have also been observed, varying based on molecular weight and methoxylation degree. Safety data for Comarum palustre is currently limited but suggests no major issues. There are no recorded drug interactions at present, though further research would be beneficial to fully understand its safety profile and potential interactions.

At a glance
Best evidence
B
Cautions
—

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • Comarum palustre L. treatment resulted in pain reduction, improvement in OA symptoms and disability, along with changes in cholesterol levels and cytokine concentrations in patients with knee OA and diabetes mellitus. B PMID
  • The study identified metabolic adaptations in hydrophytes like Comarum palustre, including increased dicarboxylic acids and soluble sugars, suggesting strategies for oxygen deficiency management. D PMID
  • The study presents a genome sequence of Comarum palustre with 37,459 annotated protein-coding genes. D PMID
  • The study found that the rheological properties of Ca-gels from Comarum palustre pectin varied based on molecular weight and methoxylation degree. D PMID

Frequently asked questions

What is Marsh Cinquefoil?

Marsh Cinquefoil (Comarum palustre) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Marsh Cinquefoil?

4 sourced findings are recorded for Marsh Cinquefoil; the strongest carries evidence grade B. For example: Comarum palustre L. treatment resulted in pain reduction, improvement in OA symptoms and disability, along with changes in cholesterol levels and cytokine concentrations in patients with knee OA and diabetes mellitus.

How strong is the evidence for Marsh Cinquefoil?

The strongest finding for Marsh Cinquefoil carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).

Is Marsh Cinquefoil safe? What are the side effects?

No major safety issues are recorded for Marsh Cinquefoil in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Marsh Cinquefoil interact with medications?

No drug interactions are recorded for Marsh Cinquefoil in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Marsh Cinquefoil?

Marsh Cinquefoil is also known as: Сабельник болотный, Comaret des marais, Potentille des marais.

Is Marsh Cinquefoil a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 Pleiotropic Effects of Comarum palustre L. in Patients with Osteoarthritis and Diabetes Mellitus with High Comorbidity Burden: An Exploratory Study. literature abstract metadata
  2. T2 Complex influence of structural characteristics of low-methoxyl pectins on rheological properties of semi-solid Ca-gels. literature abstract metadata
  3. T2 The genome sequence of the marsh cinquefoil, Comarum palustre L., also known as Potentilla palustris (L.) Scop. (Rosaceae). literature abstract metadata
  4. T2 Metabolite Profiling of Leaves of Irises and Cinquefoils of Hydrophytic and Mesophytic Nature. literature abstract metadata