Myrrh

Commiphora

Commiphora is a genus of plants traditionally used in various forms of traditional medicine, particularly in Ayurveda and Unani systems. While specific uses for Commiphora species are not extensively documented, studies suggest potential anesthetic properties for Anacyclus pyrethrum and Commiphora myrrha based on phytochemical, cytotoxic, and molecular docking analyses. Guggulsterone from Commiphora mukul shows promise in modulating the FXR axis, influencing bile acid metabolism and potentially addressing metabolic disturbances through its effects on CYP enzymes and transporters. Additionally, a mixture involving Boswellia serrata, Commiphora myrrha, propolis, and Scutellaria baicalensis has been observed to reduce chemokine expression in canine keratinocytes. Safety data for Commiphora species indicate no major issues have been recorded, and there are currently no reported drug interactions.

At a glance
Best evidence
D
Cautions

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • Phytochemical, cytotoxic, and molecular docking analyses suggest potential anesthetic properties for Anacyclus pyrethrum and Commiphora myrrha. D PMID
  • Guggulsterone from Commiphora mukul modulates FXR and PXR, influencing CYP enzymes and transporters. D PMID
  • A mixture of Boswellia serrata, Commiphora myrrha, propolis, and Scutellaria baicalensis reduced chemokine expression in canine keratinocytes. D PMID
  • Guggulsterone from Commiphora mukul modulates the FXR axis, influencing bile acid metabolism and potentially addressing metabolic disturbances. D PMID
  • Emerging evidence suggests that yogic interventions and Ayurveda-based herbal medicines may offer potential benefits in managing hypothyroidism and its neuropsychiatric manifestations, but current evidence remains preliminary. D PMID

Frequently asked questions

What is Myrrh?

Myrrh (Commiphora) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Myrrh?

5 sourced findings are recorded for Myrrh; the strongest carries evidence grade D. For example: Phytochemical, cytotoxic, and molecular docking analyses suggest potential anesthetic properties for Anacyclus pyrethrum and Commiphora myrrha.

How strong is the evidence for Myrrh?

The strongest finding for Myrrh carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Myrrh safe? What are the side effects?

No major safety issues are recorded for Myrrh in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Myrrh interact with medications?

No drug interactions are recorded for Myrrh in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Myrrh?

Myrrh is also known as: Коммифора.

Is Myrrh a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 A Botanical Mixture of Boswellia serrata, Commiphora myrrha, Propolis and Scutellaria baicalensis Reduces Expression of Inflammatory Chemokines in Canine Keratinocytes In Vitro. literature abstract metadata
  2. T2 Guggulsterone-Mediated Selective Modulation of Nuclear Receptors: Implications for FXR-PXR Signaling and Hepatic Metabolic Homeostasis. literature abstract metadata
  3. T2 Alternative and Complementary Therapies: A Review Exploring the Role of Yoga and Ayurveda-based Herbal Medicines in Alleviating Hypothyroidism and Its Neuropsychiatric Manifestations. literature abstract metadata
  4. T2 Guggulsterone as a modulator of the microbiota-bile acid-FXR axis: Molecular mechanisms and therapeutic potential in metabolic ageing. literature abstract metadata
  5. T2 Evaluation of phytochemical components, cytotoxicity, and molecular docking of Anacyclus pyrethrum and Commiphora myrrha for formulating a herbal topical anaesthetic gel development. literature abstract metadata