Yellow Vine
Coscinium fenestratum
Coscinium fenestratum, also known as Maramanjal or Daruharidra, is a traditional plant primarily used in Ayurvedic and Unani medicine. While its specific uses are not well-documented, studies suggest potential therapeutic applications against SARS-CoV-2 through network pharmacology and molecular simulations, identifying 11 active compounds that interact with key genes related to ulcerative colitis. DNA barcoding has been useful in differentiating genuine samples from adulterated ones, particularly when marketed under the name Maramanjal/Daruharidra. Scientific evidence is limited but indicates possible interactions at the molecular level. No significant safety concerns or known drug interactions have been recorded, though further research is warranted to confirm these findings and explore its full potential comprehensively.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- This study identifies potential therapeutic targets of Coscinium fenestratum alkaloids against SARS-CoV-2 through network pharmacology and molecular simulations.
- DNA barcoding helped identify genuine and adulterated samples among marketed Coscinium fenestratum and Berberis aristata under the trade name Maramanjal/Daruharidra.
- The study identified 11 active CFAs that interactively interfere with 10 key genes related to ulcerative colitis.
- The study identified a SNP marker that differentiates male from female Coscinium fenestratum individuals.
Frequently asked questions
What is Yellow Vine?
Yellow Vine (Coscinium fenestratum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Yellow Vine?
4 sourced findings are recorded for Yellow Vine; the strongest carries evidence grade D. For example: This study identifies potential therapeutic targets of Coscinium fenestratum alkaloids against SARS-CoV-2 through network pharmacology and molecular simulations.
How strong is the evidence for Yellow Vine?
The strongest finding for Yellow Vine carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Yellow Vine safe? What are the side effects?
No major safety issues are recorded for Yellow Vine in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Yellow Vine interact with medications?
No drug interactions are recorded for Yellow Vine in our sources. This does not rule them out — check with a pharmacist.
Is Yellow Vine a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Gender specific SNP markers in Coscinium fenestratum (Gaertn.) Colebr. for resource augmentation. literature abstract metadata
- T2 Exploring the Therapeutic Potentials and Molecular Mechanisms of Coscinium fenestratum Alkaloids in Ulcerative Colitis: An Integrative Network Pharmacology and Molecular Docking Approach. literature abstract metadata
- T2 Integrating macro-microscopy, DNA barcoding and HPTLC for quality assessment of berberine containing botanicals traded as Maramanjal/Daruharidra. literature abstract metadata
- T2 Integrative network pharmacology and molecular simulation analysis reveals the therapeutic potential of Coscinium fenestratum alkaloids against SARS-CoV-2. literature abstract metadata