Cyclocybe aegerita
Cyclocybe aegerita
Cyclocybe aegerita is a mushroom traditionally not associated with any specific medicinal or traditional use. Scientific studies have shown that compounds from related species, such as Cylindracin and terpene synthase Agr2 from Cyclocybe cylindracea (which may also apply to Cyclocybe aegerita), exhibit antifungal activity against certain filamentous fungi but not yeasts or bacteria. Additionally, research has identified Capebp genes in Cyclocybe aegerita that are involved in fruiting body regeneration and have shown enhanced expression of unspecific peroxygenase through genetic modifications. While these findings suggest potential biotechnological applications, there is currently no substantial evidence supporting medicinal uses for Cyclocybe aegerita itself. Safety concerns do not appear to be significant based on the available data, nor are any drug interactions recorded.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Cylindracin, a Cys-rich protein from Cyclocybe cylindracea, inhibits growth of some filamentous fungi but not yeasts or bacteria.
- The study found that the terpene synthase Agr2 from Cyclocybe aegerita can produce both a known sesquiterpene and a novel diterpene.
- The expression of a mutant unspecific peroxygenase from Cyclocybe aegerita was significantly enhanced through gene copy number increase and co-expression optimization, achieving up to 117.3 U/mL activity.
- The study identified four Capebp genes (Capebp1, Capebp3, Capebp4, and Capebp5) in Cyclocybe aegerita, with overexpression of Capebp1 or Capebp5 inducing fruiting body regeneration.
Frequently asked questions
What is Cyclocybe aegerita?
Cyclocybe aegerita (Cyclocybe aegerita) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Cyclocybe aegerita?
4 sourced findings are recorded for Cyclocybe aegerita; the strongest carries evidence grade D. For example: Cylindracin, a Cys-rich protein from Cyclocybe cylindracea, inhibits growth of some filamentous fungi but not yeasts or bacteria.
How strong is the evidence for Cyclocybe aegerita?
The strongest finding for Cyclocybe aegerita carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Cyclocybe aegerita safe? What are the side effects?
No major safety issues are recorded for Cyclocybe aegerita in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Cyclocybe aegerita interact with medications?
No drug interactions are recorded for Cyclocybe aegerita in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Cyclocybe aegerita?
Cyclocybe aegerita is also known as: Pholiote du peuplier.
Is Cyclocybe aegerita a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Enhancing the expression of the unspecific peroxygenase in Komagataella phaffii through a combination strategy. literature abstract metadata
- T2 Characterization of PEBP-like Genes and Function of Capebp1 and Capebp5 in Fruiting Body Regeneration in Cyclocybe aegerita. literature abstract metadata
- T2 Bifunctional Sesquiterpene/Diterpene Synthase Agr2 from Cyclocybe aegerita Gives Rise to the Novel Diterpene Cyclocybene. literature abstract metadata
- T2 Cylindracin, a Cys-rich protein expressed in the fruiting body of Cyclocybe cylindracea, inhibits growth of filamentous fungi but not yeasts or bacteria. literature abstract metadata