Calyx-shaped Tigernanmu
Daphniphyllum calycinum
Daphniphyllum calycinum is a plant traditionally used in East Asian medicine but lacks specific traditional uses documented. Scientific evidence suggests that compounds from D. calycinum may alleviate gastric mucosal injury by regulating autophagy and targeting the TLR4/NF-κB/NLRP3 pathway, though more research is needed to confirm these findings. The plant also shows antienteroviral activity against EV71 with two compounds demonstrating superior efficacy compared to ribavirin; however, further studies are required for broader validation. Notably, D. calycinum has been used in a bionic broach design that showed reduced cutting forces and improved chip management, but this application is unrelated to its potential medicinal uses. Safety profiles indicate no major issues have been recorded, and there are currently no reported drug interactions associated with the plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study identified two compounds from Daphniphyllum calycinum with potent antiviral effects against Enterovirus 71 in RD cells.
- DCPH alleviates gastric mucosal injury by regulating autophagy and targeting the TLR4/NF-κB/NLRP3 pathway.
- The study found that Daphniphyllum calycinum had a mean inclination angle of 31.22° among four tree species measured using a deep learning approach.
- The study found that bionic broaches imitating Daphniphyllum calycinum had reduced cutting forces and improved chip management, though results varied with different designs.
- Ten new Daphniphyllum alkaloids were identified, with some showing bioactivity in cell models.
Frequently asked questions
What is Calyx-shaped Tigernanmu?
Calyx-shaped Tigernanmu (Daphniphyllum calycinum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Calyx-shaped Tigernanmu?
5 sourced findings are recorded for Calyx-shaped Tigernanmu; the strongest carries evidence grade D. For example: The study identified two compounds from Daphniphyllum calycinum with potent antiviral effects against Enterovirus 71 in RD cells.
How strong is the evidence for Calyx-shaped Tigernanmu?
The strongest finding for Calyx-shaped Tigernanmu carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Calyx-shaped Tigernanmu safe? What are the side effects?
No major safety issues are recorded for Calyx-shaped Tigernanmu in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Calyx-shaped Tigernanmu interact with medications?
No drug interactions are recorded for Calyx-shaped Tigernanmu in our sources. This does not rule them out — check with a pharmacist.
Is Calyx-shaped Tigernanmu a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Calycindaphines A-J, Daphniphyllum alkaloids from the roots of Daphniphyllum calycinum. literature abstract metadata
- T2 Assessment of a Bionic Broach Implanted with Nylon Fibers. literature abstract metadata
- T2 Estimating canopy leaf angle from leaf to ecosystem scale: a novel deep learning approach using unmanned aerial vehicle imagery. literature abstract metadata
- T2 Cyano-containing Daphniphyllum alkaloids with antienteroviral activity from the leaves and stems of Daphniphyllum calycinum Benth. literature abstract metadata
- T2 The Herbal Pair Daphniphyllum calycinum-Polygonum hydropiper Alleviates Gastric Mucosal Injury via Regulating Autophagy and Targeting the TLR4/NF-κB/NLRP3 Pathway. literature abstract metadata