Diospyros malabarica
Diospyros malabarica
Diospyros malabarica, a traditional plant known for its fruit, has not been extensively documented in historical or current traditional medicine practices. Scientific studies have shown that fruit preparations of Diospyros malabarica (DFP) may upregulate TH1 cytokine secretion and p53 expression while downregulating TH2 cytokines, potentially offering tumor protective benefits. Additionally, the methanol extract from its fruit demonstrated anti-inflammatory effects by modulating pro- and anti-inflammatory biomarkers in rat models. The bark of Diospyros malabarica has also been studied, with methanol being the most effective solvent for extracting phytochemicals and biological activities. Quercetin found in the fruits showed potential hepatoprotective effects by influencing liver function parameters and signaling proteins in rats. Safety concerns are currently minimal as no major issues have been recorded. Similarly, there is no evidence of significant drug interactions reported. However, further research is needed to fully understand its safety profile and broader applications.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Diospyros malabarica fruit preparation (DFP) upregulates TH1 cytokine secretion and p53 expression while downregulating TH2 cytokines, potentially evoking tumor protective immunity.
- The methanol extract of Diospyros malabarica fruit showed anti-inflammatory effects by modulating pro- and anti-inflammatory biomarkers in rat models.
- The study found that quercetin from Diospyros malabarica fruits showed potential hepatoprotective effects by modulating liver function parameters and signaling proteins in rats.
- The study found that methanol was the most effective solvent for extracting phytochemicals and biological activities from Diospyros malabarica bark.
Frequently asked questions
What is Diospyros malabarica?
Diospyros malabarica (Diospyros malabarica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Diospyros malabarica?
4 sourced findings are recorded for Diospyros malabarica; the strongest carries evidence grade D. For example: Diospyros malabarica fruit preparation (DFP) upregulates TH1 cytokine secretion and p53 expression while downregulating TH2 cytokines, potentially evoking tumor protective immunity.
How strong is the evidence for Diospyros malabarica?
The strongest finding for Diospyros malabarica carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Diospyros malabarica safe? What are the side effects?
No major safety issues are recorded for Diospyros malabarica in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Diospyros malabarica interact with medications?
No drug interactions are recorded for Diospyros malabarica in our sources. This does not rule them out — check with a pharmacist.
Is Diospyros malabarica a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Nonlinear molecular dynamics of quercetin in Gynocardia odorata and Diospyros malabarica fruits: Its mechanistic role in hepatoprotection. literature abstract metadata
- T2 A Comparative Study of Diospyros malabarica (Gaub) Extracts in Various Polarity-Dependent Solvents for Evaluation of Phytoconstituents and Biological Activities. literature abstract metadata
- T2 Diospyros malabarica (Desr.) Kostel fruits extract attenuated acute and chronic inflammation through modulation of the expression of pro- and anti-inflammatory biomarkers in rat models. literature abstract metadata
- T2 Diospyros malabarica fruit preparation mediates immunotherapeutic modulation and epigenetic regulation to evoke protection against non-small cell lung cancer (NSCLC). literature abstract metadata