mangrove trumpet tree
Dolichandrone spathacea
Dolichandrone spathacea is a plant traditionally not known for any specific medicinal uses. Scientific studies have identified key phytochemicals, including iridoids and potential α-glucosidase inhibitors, which may hold promise in treating chronic bronchitis by modulating TNF and IL-17 signaling pathways. Additionally, the mitochondrial and chloroplast genomes of Dolichandrone spathacea were compared to its terrestrial relative, revealing differences that could aid in species distinction and understanding evolutionary adaptation. The leaf extracts showed potential XO inhibition with identified compounds having IC50 values ranging from 19.34 μM to 64.50 μM. No major safety issues or drug interactions have been recorded for Dolichandrone spathacea, though further research is necessary to fully understand its potential benefits and applications.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study identified and synthesized iridoids from Dolichandrone spathacea, finding that compound 10 shows strong α-glucosidase inhibition.
- This study identified key phytochemicals and potential mechanisms of Dolichandrone spathacea in treating chronic bronchitis by modulating TNF and IL-17 signaling pathways.
- The study found that while mitochondrial genomes differ in size between Dolichandrone spathacea and its terrestrial relative, chloroplast genomes are more similar, with some regions showing high divergence.
- The leaf extract of Dolichandrone spathacea inhibits xanthine oxidase activity at 100 µg/mL, with some compounds showing competitive or mixed-type inhibition.
Frequently asked questions
What is mangrove trumpet tree?
mangrove trumpet tree (Dolichandrone spathacea) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about mangrove trumpet tree?
4 sourced findings are recorded for mangrove trumpet tree; the strongest carries evidence grade D. For example: The study identified and synthesized iridoids from Dolichandrone spathacea, finding that compound 10 shows strong α-glucosidase inhibition.
How strong is the evidence for mangrove trumpet tree?
The strongest finding for mangrove trumpet tree carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is mangrove trumpet tree safe? What are the side effects?
No major safety issues are recorded for mangrove trumpet tree in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does mangrove trumpet tree interact with medications?
No drug interactions are recorded for mangrove trumpet tree in our sources. This does not rule them out — check with a pharmacist.
Is mangrove trumpet tree a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Isolation, semi-synthesis, docking-based prediction, and bioassay-based activity of Dolichandrone spathacea iridoids: new catalpol derivatives as glucosidase inhibitors. literature abstract metadata
- T2 Xanthine oxidase inhibition study of isolated secondary metabolites from Dolichandrone spathacea (Bignoniaceae): In vitro and in silico approach. literature abstract metadata
- T2 Comparison of organelle genomes between endangered mangrove plant Dolichandrone spathacea to terrestrial relative provides insights into its origin and adaptative evolution. literature abstract metadata
- T2 Isolation of phytochemicals and exploration the mechanism of Dolichandrone spathacea in the treatment of chronic bronchitis by integrating network pharmacology, molecular docking, and experimental validation. literature abstract metadata