Burningbush
Euonymus alatus
Euonymus alatus, commonly known as winged spindle tree, is a traditional medicine with origins in East Asia. While it has been used in various folk remedies, specific traditional uses for this plant are not well-documented. Scientific studies have shown promising results, indicating that the leaf ethanol extract of Euonymus alatus exhibits strong antioxidant, antidiabetic, and anticancer effects in vitro. Additionally, it extended lifespan in tumor-bearing mice and showed protective effects against oxidative stress-induced damage in cells. The treatment also improved memory impairment in mice by reducing oxidative stress markers. Notably, research has also contributed to the understanding of the mitochondrial genome structure of related plants like Tripterygium wilfordii through annotation of RNA editing events. As for safety, no major issues have been recorded, and there are currently no reported drug interactions associated with this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study found that Euonymus alatus leaf ethanol extract showed strong antioxidant, antidiabetic, and anticancer effects in vitro and extended lifespan in tumor-bearing mice.
- Euonymus alatus leaves and their compounds showed protective effects against hydrogen peroxide-induced oxidative stress in HT22 cells by modulating apoptosis-related markers and increasing antioxidant enzyme levels.
- PCA treatment improved scopolamine-induced memory impairment and reduced oxidative stress markers in mice.
- The study assembled and annotated the mitochondrial genome of Tripterygium wilfordii, revealing its structure and RNA editing events.
Frequently asked questions
What is Burningbush?
Burningbush (Euonymus alatus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Burningbush?
4 sourced findings are recorded for Burningbush; the strongest carries evidence grade D. For example: The study found that Euonymus alatus leaf ethanol extract showed strong antioxidant, antidiabetic, and anticancer effects in vitro and extended lifespan in tumor-bearing mice.
How strong is the evidence for Burningbush?
The strongest finding for Burningbush carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Burningbush safe? What are the side effects?
No major safety issues are recorded for Burningbush in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Burningbush interact with medications?
No drug interactions are recorded for Burningbush in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Burningbush?
Burningbush is also known as: бересклет крылатый.
Is Burningbush a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Protocatechuic Acid from Euonymus alatus Mitigates Scopolamine-Induced Memory Impairment in Mice. literature abstract metadata
- T2 Euonymus alatus and its compounds suppress hydrogen peroxide-induced oxidative stress in HT22 cells. literature abstract metadata
- T2 Bioactivity Evaluation and Phytochemical Characterization of Euonymus alatus (Thunb.) Siebold Leaf Extract. literature abstract metadata
- T2 De Novo Hybrid Assembly of the Tripterygium wilfordii Mitochondrial Genome Provides the Chromosomal Mitochondrial DNA Structure and RNA Editing Events. literature abstract metadata