FolkKB

Eupatorium perfoliatum

Eupatorium perfoliatum

Eupatorium perfoliatum, commonly known as boneset, is a traditional medicinal plant used in North American herbal practices. It has been traditionally employed for treating fever and digestive complaints. Scientific studies suggest potential benefits, including an ultradiluted hydroethanolic preparation that may help reduce symptoms associated with Chikungunya virus infection by modulating TNF-α. The plant was also identified as one of 14 locally used medicinal plants in Eastern Kentucky with possible antimicrobial, anticancer, antioxidant, and anti-inflammatory properties. Additionally, research indicates that Eupatorium perfoliatum 30C may offer some protection against probable and laboratory-confirmed dengue. Safety-wise, no major issues have been recorded, and there are currently no known drug interactions associated with its use.

At a glance
Traditionally for
fever · digestive complaints
Traditions
Western phytotherapy
Best evidence
D
Cautions
—

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

Traditional use

What the science says

  • This study suggests that an ultradiluted hydroethanolic preparation of Eupatorium perfoliatum may help reduce symptoms associated with Chikungunya virus infection by interacting with TNF-α. D PMID
  • The study found that Eupatorium perfoliatum, among other local plants, showed various pharmacological activities like antimicrobial, anticancer, antioxidant, and anti-inflammatory effects. D PMID
  • UDE treatment suppressed inflammatory cell infiltration, tissue-level oxidative stress, and mitochondrial damage in SARS-CoV-2 S protein-induced lung pathogenesis. D PMID
  • The study found that Eupatorium perfoliatum 30C was associated with some protection against probable and laboratory-confirmed dengue. D PMID

Frequently asked questions

What is Eupatorium perfoliatum?

Eupatorium perfoliatum (Eupatorium perfoliatum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What is Eupatorium perfoliatum traditionally used for?

Traditional sources record Eupatorium perfoliatum for: fever, digestive complaints. This reflects traditional use, not a proven medical treatment.

Which traditions use Eupatorium perfoliatum?

Eupatorium perfoliatum appears in these traditions in our sources: Western phytotherapy.

What does the scientific evidence say about Eupatorium perfoliatum?

4 sourced findings are recorded for Eupatorium perfoliatum; the strongest carries evidence grade D. For example: This study suggests that an ultradiluted hydroethanolic preparation of Eupatorium perfoliatum may help reduce symptoms associated with Chikungunya virus infection by interacting with TNF-α.

How strong is the evidence for Eupatorium perfoliatum?

The strongest finding for Eupatorium perfoliatum carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Eupatorium perfoliatum safe? What are the side effects?

No major safety issues are recorded for Eupatorium perfoliatum in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Eupatorium perfoliatum interact with medications?

No drug interactions are recorded for Eupatorium perfoliatum in our sources. This does not rule them out — check with a pharmacist.

Is Eupatorium perfoliatum a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 Effectiveness of Eupatorium Perfoliatum 30C in Preventing Dengue Fever-A Prospective, Community-Based, Open Label, Parallel Cohort Study in Delhi, India. literature abstract metadata
  2. T2 Ultradiluted Eupatorium perfoliatum Prevents and Alleviates SARS-CoV-2 Spike Protein-Induced Lung Pathogenesis by Regulating Inflammatory Response and Apoptosis. literature abstract metadata
  3. T2 A Review and Survey of Local Eastern Kentucky Medicinal Plants and Their Pharmacological Benefits. literature abstract metadata
  4. T2 Eupatorium perfoliatum Counteracts TNF-α Mediated Pathogenesis in Chikungunya Virus Infection. literature abstract metadata
  5. T3 Eupatorium perfoliatum CC BY-SA 4.0