Devil's Walking Stick
Euphorbia lactea
Euphorbia lactea is a plant traditionally found in tropical and subtropical regions of Asia. While it has not been extensively used in traditional medicine, studies have identified nine diterpenoids from Euphorbia lactea that show potential anti-HIV-1 activity, with two compounds demonstrating significant effects. Additionally, an ethanolic extract from Euphorbia nivulia (which may be closely related or a similar species) exhibited concentration-dependent anticonvulsant properties and reduced epileptogenesis in mice. Genetic variations between normal and fasciated stem segments of Euphorbia lactea have been observed through RAPD fingerprints and protein analysis, highlighting the importance of genetic diversity within the species. Although promising, the effects are influenced by structural differences among compounds from related species. No major safety concerns or drug interactions have been recorded for Euphorbia lactea to date.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Genetic variations between normal and fasciated stem segments were observed in Euphorbia lactea through RAPD fingerprints and SDS-PAGE analysis.
- Nine diterpenoids were identified from Euphorbia lactea, with two showing anti-HIV-1 activity.
- Euphorbia nivulia extract showed concentration-dependent anticonvulsant effects and reduced epileptogenesis in mice.
- The study identified a compound from Euphorbia lactea with potential for HIV-1 reactivation, but findings are preliminary.
Frequently asked questions
What is Devil's Walking Stick?
Devil's Walking Stick (Euphorbia lactea) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Devil's Walking Stick?
4 sourced findings are recorded for Devil's Walking Stick; the strongest carries evidence grade D. For example: Genetic variations between normal and fasciated stem segments were observed in Euphorbia lactea through RAPD fingerprints and SDS-PAGE analysis.
How strong is the evidence for Devil's Walking Stick?
The strongest finding for Devil's Walking Stick carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Devil's Walking Stick safe? What are the side effects?
No major safety issues are recorded for Devil's Walking Stick in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Devil's Walking Stick interact with medications?
No drug interactions are recorded for Devil's Walking Stick in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Devil's Walking Stick?
Devil's Walking Stick is also known as: Молочай молочный, Cactus candélabre.
Is Devil's Walking Stick a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Effects of diterpenes from latex of Euphorbia lactea and Euphorbia laurifolia on human immunodeficiency virus type 1 reactivation. literature abstract metadata
- T2 Stem fasciation in cacti and succulent species--tissue anatomy, protein pattern and RAPD polymorphisms. literature abstract metadata
- T2 Evaluation of anticonvulsant and antiepileptogenic activity of Euphorbia nivulia in PTZ-induced kindling model of epilepsy in mice. literature abstract metadata
- T2 Diterpenoids from Euphorbia lactea and their anti-HIV-1 activity. literature abstract metadata