Euphorbia milii

Euphorbia milii

Euphorbia milii, commonly known as the crown of thorns, is a plant native to Madagascar. Traditionally, its use in medicine has not been documented; however, it has gained attention for its diverse pharmacological activities. Scientific studies have identified over 85 compounds from Euphorbia milii, including terpenoids with potential anti-rheumatic activity and diterpenoids that bind to RORγt, suggesting possible immunomodulatory effects. Additionally, nickel oxide nanoparticles synthesized using extracts of this plant exhibit varying antibacterial, antioxidant, anti-inflammatory, and antidiabetic activities. While the evidence is promising, more research is needed to confirm these findings comprehensively. Notably, no significant safety concerns or drug interactions have been recorded for Euphorbia milii, but further investigation is warranted to fully understand its potential benefits and risks.

At a glance
Best evidence
D
Cautions

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • 85 compounds have been identified from Euphorbia milii with diverse pharmacological activities including analgesic, anti-inflammatory, antioxidant, antimicrobial, anticancer, and others. D PMID
  • The study found that nickel oxide nanoparticles synthesized from different plant species showed varying antibacterial, antioxidant, anti-inflammatory, and antidiabetic activities. D PMID
  • Seven terpenoids were isolated from Euphorbia milii, with two abietane-type diterpenoids showing potential anti-rheumatic activity. D PMID
  • Ten diterpenoids were isolated from Euphorbia milii, with three showing binding to RORγt. D PMID

Frequently asked questions

What is Euphorbia milii?

Euphorbia milii (Euphorbia milii) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Euphorbia milii?

4 sourced findings are recorded for Euphorbia milii; the strongest carries evidence grade D. For example: 85 compounds have been identified from Euphorbia milii with diverse pharmacological activities including analgesic, anti-inflammatory, antioxidant, antimicrobial, anticancer, and others.

How strong is the evidence for Euphorbia milii?

The strongest finding for Euphorbia milii carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Euphorbia milii safe? What are the side effects?

No major safety issues are recorded for Euphorbia milii in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Euphorbia milii interact with medications?

No drug interactions are recorded for Euphorbia milii in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Euphorbia milii?

Euphorbia milii is also known as: Молочай Миля.

Is Euphorbia milii a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 Plant-mediated nickel oxide nanoparticles show species-dependent antibacterial, antioxidant, anti-inflammatory and antidiabetic activities. literature abstract metadata
  2. T2 Structurally diverse diterpenoids from Euphorbia milii: Discovery and RORγt-binding evaluation. literature abstract metadata
  3. T2 Traditional Herbal Medicine Euphorbia milii Des Moul: Research progress in chemical constituents and pharmacological activities. literature abstract metadata
  4. T2 Terpenoids in Euphorbia milii Ch. des Moulins and their anti-rheumatic potential. literature abstract metadata