FICVER

Ficaria verna

Ficaria verna, commonly known as lesser celandine or pilewort, is a traditional European plant with historical significance. It has been used in folk medicine for various conditions but specific traditional uses are not well-documented. Scientific studies have shown that extracts from Ficaria verna can enhance proinflammatory cytokine production in respiratory epithelial cell lines, indicating potential relevance to respiratory health. However, the evidence is preliminary and more research is needed to confirm these findings. Additionally, Podosphaera fusca and Peronospora ficariae, which are associated with Ficaria verna, have been found to induce significant cytokine production, increase IgE levels, and cause histological changes in mouse lungs, suggesting they may act as inhalant allergens. The plant has also demonstrated effectiveness in treating and preventing scurvy due to its vitamin C content. Lesser celandine's flower closure mechanism helps protect pollen from rain-induced loss and maintains higher viability. No major safety concerns or known drug interactions have been recorded for Ficaria verna, though further research is warranted to fully understand its potential benefits and risks.

At a glance
Best evidence
D
Cautions

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • P. ficariae extracts significantly enhanced proinflammatory cytokine production in respiratory epithelial cell lines. D PMID
  • Podosphaera fusca and Peronospora ficariae induced significant cytokine production, increased IgE levels, and caused histological changes in mouse lungs, suggesting they may be inhalant allergens. D PMID
  • The study found that Ficaria verna and other green plants showed effectiveness in treating and preventing scurvy. D PMID
  • Flower closure in lesser celandine helps protect pollen from rain-induced loss and maintains higher viability. D PMID

Frequently asked questions

What is FICVER?

FICVER (Ficaria verna) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about FICVER?

4 sourced findings are recorded for FICVER; the strongest carries evidence grade D. For example: P. ficariae extracts significantly enhanced proinflammatory cytokine production in respiratory epithelial cell lines.

How strong is the evidence for FICVER?

The strongest finding for FICVER carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is FICVER safe? What are the side effects?

No major safety issues are recorded for FICVER in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does FICVER interact with medications?

No drug interactions are recorded for FICVER in our sources. This does not rule them out — check with a pharmacist.

What are the common names of FICVER?

FICVER is also known as: чистяк весенний, Ficaire.

Is FICVER a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 [Scurvy-A now forgotten previously widespread disease]. literature abstract metadata
  2. T2 Floral Closure in Lesser Celandine (Ficaria verna) Protects Anthers from Pollen Flushing and Preserves Pollen Viability. literature abstract metadata
  3. T2 Microfungus Podosphaera fusca and the Fungus-like Organism Peronospora ficariae as Potential Inhalant Allergens in a Mouse Model of Asthma. literature abstract metadata
  4. T2 In vitro Study of Fungus-Like Organisms Peronospora ficariae and Wilsoniana bliti as Potential Inhalant Allergens. literature abstract metadata