Ash
Fraxinus
Fraxinus is a plant traditionally not associated with any specific medicinal uses. Scientific research has shown that Fraxinus bark fraction (BFM) demonstrated significant reduction in inflammatory markers and improvement in redox balance in a Caco-2/RAW264.7 co-culture model, suggesting potential anti-inflammatory properties. Additionally, studies on Fraxinus mandshurica have indicated enhanced drought tolerance through the promotion of lignin biosynthesis and activation of the phenylpropanoid pathway. A dioxygenase from Fraxinus chinensis (FcDOH2) was found to exhibit substrate-dependent bifunctionality in catalyzing O-demethylation and C8-hydroxylation of coumarins, contributing to our understanding of its biochemical functions. The research also developed prediction models for tree height and height-to-crown base using TLS data, enhancing accuracy through the inclusion of multiple ecological factors. No major safety concerns or recorded drug interactions have been noted thus far.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- BFM from Fraxinus showed significant reduction in inflammatory markers and improvement in redox balance in a Caco-2/RAW264.7 co-culture model.
- Overexpression of Fraxinus mandshurica SPL2 enhances drought tolerance by promoting lignin biosynthesis and activating the phenylpropanoid pathway.
- A Fraxinus chinensis dioxygenase (FcDOH2) exhibits substrate-dependent bifunctionality, catalyzing O-demethylation and C8-hydroxylation of coumarins.
- The study developed prediction models for tree height and height to crown base of Fraxinus mandshurica, Juglans mandshurica, and Phellodendron amurense using TLS data, improving accuracy through the inclusion of multiple ecological factors.
- Fraxinus xanthoxyloides bark methanol extract showed potential anti-diabetic effects in alloxan-induced diabetic rats through multiple mechanisms.
- Mixed-species afforestation increased soil carbon and nitrogen storage more than monocultures, primarily due to higher proportions of larger aggregates.
Frequently asked questions
What is Ash?
Ash (Fraxinus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Ash?
6 sourced findings are recorded for Ash; the strongest carries evidence grade D. For example: BFM from Fraxinus showed significant reduction in inflammatory markers and improvement in redox balance in a Caco-2/RAW264.7 co-culture model.
How strong is the evidence for Ash?
The strongest finding for Ash carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Ash safe? What are the side effects?
No major safety issues are recorded for Ash in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Ash interact with medications?
No drug interactions are recorded for Ash in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Ash?
Ash is also known as: ясень, frêne.
Is Ash a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Fraxinus mandshurica SPL2 enhances tolerance to drought stress by activating the phenylpropanoid pathway. literature abstract metadata
- T2 Anti-Inflammatory Activity of In Vitro Digested Manna in a Caco-2 and RAW264.7 Cells Co-Culture Model of Inflammatory Bowel Disease. literature abstract metadata
- T2 [Prediction models for tree height and height to crown base of individual trees in valuable hardwood broad-leaved forests of Northeast China based on terrestrial laser scanning data]. literature abstract metadata
- T2 Protective effects of Fraxinus xanthoxyloides bark in alloxan-induced diabetic rats: A phytochemical and pharmacological approach. literature abstract metadata
- T2 A Substrate-Dependent Bifunctional Dioxygenase from Fraxinus chinensis for O-Demethylation and C8-Hydroxylation of Coumarins. literature abstract metadata
- T2 Mixed-species afforestation stimulates the flow and turnover of carbon and nitrogen within soil aggregates in a degraded karst ecosystem. literature abstract metadata