Gardenia saxatilis
Gardenia saxatilis
Gardenia saxatilis is a plant traditionally not associated with any specific medicinal uses. Scientific studies have shown that a novel compound from Hypoxylon saxatilis KKU-KHP 01 demonstrated inhibitory activity against Ralstonia solanacearum, effectively reducing tomato wilt disease severity by up to 83.33% in greenhouse conditions. Additionally, four compounds isolated from Gardenia saxatilis exhibited weak antiplasmodial activity with IC50 values ranging between 1.5 and 3.8 microg/ml, indicating potential for use against malaria parasites. Notably, clerodane diterpenes and their methyl esters from Aquarius grandiflorus showed promising antiparasitic activity against Trypanosoma cruzi, while a mixture of eight triterpenic esters targeted PfA-M17 in Plasmodium falciparum, displaying antiplasmodial activity. To date, no significant safety concerns or drug interactions have been reported for Gardenia saxatilis.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- A novel compound from Hypoxylon saxatilis KKU-KHP 01 showed inhibitory activity against R. solanaceum, reducing tomato wilt disease severity by up to 83.33% in greenhouse conditions.
- Four compounds from Gardenia saxatilis exhibited weak antiplasmodial activity, with IC50 values ranging from 1.5 to 3.8 microg/ml.
- The study found that clerodane diterpenes and their methyl esters from Aquarius grandiflorus showed potential antiparasitic activity against Trypanosoma cruzi.
- The study identified that a mixture of eight triterpenic esters targets PfA-M17 in Plasmodium falciparum, showing antiplasmodial activity.
Frequently asked questions
What is Gardenia saxatilis?
Gardenia saxatilis (Gardenia saxatilis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Gardenia saxatilis?
4 sourced findings are recorded for Gardenia saxatilis; the strongest carries evidence grade D. For example: A novel compound from Hypoxylon saxatilis KKU-KHP 01 showed inhibitory activity against R. solanaceum, reducing tomato wilt disease severity by up to 83.33% in greenhouse conditions.
How strong is the evidence for Gardenia saxatilis?
The strongest finding for Gardenia saxatilis carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Gardenia saxatilis safe? What are the side effects?
No major safety issues are recorded for Gardenia saxatilis in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Gardenia saxatilis interact with medications?
No drug interactions are recorded for Gardenia saxatilis in our sources. This does not rule them out — check with a pharmacist.
Is Gardenia saxatilis a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Antiplasmodial triterpenes from twigs of Gardenia saxatilis. literature abstract metadata
- T2 Anti-Trypanosoma cruzi activity of clerodane diterpenes and their methyl ester derivatives from Aquarius grandiflorus (Alismataceae). literature abstract metadata
- T2 Novel secondary metabolite from a new species of Hypoxylon saxatilis sp. nov. for suppressing bacterial wilt in tomato. literature abstract metadata
- T2 Natural triterpenic phenolic esters target PfA-M17 in Plasmodium falciparum. literature abstract metadata