FolkKB

Gingko

Ginkgo

Ginkgo (Ginkgo biloba) is a traditional medicine with roots in East Asian practices, particularly in China and Japan. It has been used for various conditions such as memory enhancement, tinnitus, and intermittent claudication, though its traditional uses are not well-documented in the literature. Preclinical studies indicate potential neuroprotective effects of Ginkgo biloba through multiple mechanisms, but clinical evidence is limited and inconclusive. Research suggests that components like quercetin and ginkgolide B may modulate complement proteins C3 and C5, which could be beneficial for conditions such as dry age-related macular degeneration. Technological advancements have improved the extraction and delivery of Ginkgo biloba's bioactive compounds. No major safety issues or drug interactions have been recorded to date, but further clinical trials are needed to substantiate its therapeutic claims fully.

At a glance
Best evidence
A
Cautions
—

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • Preclinical studies suggest Ginkgo biloba may exert neuroprotective effects through multiple mechanisms, but clinical data are insufficient for routine use. A PMID
  • The study found that GbMYB15 is a negative regulator of total flavonoid synthesis in Ginkgo biloba. D PMID
  • The study suggests that ginkgo biloba extract components, particularly quercetin and ginkgolide B, may modulate complement proteins C3 and C5, potentially benefiting dry age-related macular degeneration. D PMID
  • Recent technological innovations have improved the extraction and delivery of Ginkgo biloba extract's bioactive compounds. A PMID
  • The study identified key genes involved in cellulose, hemicellulose, and lignin biosynthesis during secondary cell wall development in Ginkgo biloba. D PMID
  • The study found that tree age is a primary negative regulator of total biflavonoid content in Ginkgo biloba leaves. D PMID
  • The study identified Ginkgo Leaf as one of the top medicinal herbs associated with adverse event patterns in GLP-1 RA therapy for obesity. D PMID
  • This study suggests that various plant extracts may offer therapeutic potential for heart failure, with different extracts showing advantages in improving cardiac function, quality of life, and prognosis. A PMID
  • The study identified key genes and cellular mechanisms involved in ginkgolic acid biosynthesis in Ginkgo biloba episperm. D PMID
  • The study found that adjuvant GLED therapy was associated with a significantly lower incidence of subacute deep vein thrombosis in elderly patients following PFNA surgery, though further research is needed. D PMID

Frequently asked questions

What is Gingko?

Gingko (Ginkgo) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Gingko?

10 sourced findings are recorded for Gingko; the strongest carries evidence grade A. For example: Preclinical studies suggest Ginkgo biloba may exert neuroprotective effects through multiple mechanisms, but clinical data are insufficient for routine use.

How strong is the evidence for Gingko?

The strongest finding for Gingko carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).

Is Gingko safe? What are the side effects?

No major safety issues are recorded for Gingko in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Gingko interact with medications?

No drug interactions are recorded for Gingko in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Gingko?

Gingko is also known as: Гинкго.

Is Gingko a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 Advanced extraction to targeted delivery: A holistic review of technological innovations and therapeutic mechanisms of Ginkgo biloba extract. literature abstract metadata
  2. T2 Ginkgo biloba as a Promising Candidate for Traumatic Brain Injury: Insights From Preclinical and Clinical Studies. literature abstract metadata
  3. T2 Complement-Modulating Mechanisms of Ginkgo biloba Extract in Dry AMD: Insights From Molecular Docking and Dynamics Simulations. literature abstract metadata
  4. T2 Identification and functional analysis of GbMYB15 as a negative regulator in flavonoid biosynthesis of Ginkgo biloba. literature abstract metadata
  5. T2 The role of ginkgo leaf extract and dipyridamole adjuvant treatment for reduction of lower limb deep vein thrombosis after proximal femoral nail antirotation surgery in elderly patients with intertrochanteric femoral fracture. literature abstract metadata
  6. T2 Single-nucleus sequencing and spatial metabolomics analysis reveal the regulatory mechanism of ginkgolic acid biosynthesis in the episperm of Ginkgo biloba. literature abstract metadata
  7. T2 Efficacy of plant extracts in heart failure patients: a systematic review and network meta-analysis. literature abstract metadata
  8. T2 Patterns of Biflavonoid Accumulation in Ginkgo (Ginkgo biloba L.) Leaves from 90 Trees and Their Variation with Age, Gender, and Location. literature abstract metadata
  9. T2 Revealing the genetic regulation of wood traits and secondary cell wall development in Ginkgo biloba: an integrated analysis from the perspectives of GWAS, TWAS, and WGCNA. literature abstract metadata
  10. T2 Real-world and computational identification of herbal candidates associated with adverse event patterns in glucagon-like peptide-1 therapy for obesity. literature abstract metadata

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