Witch-hazel
Hamamelis
Hamamelis, commonly known as witch hazel, is a traditional medicine plant used in various cultures. It has been traditionally utilized for its purported astringent and anti-inflammatory properties, particularly in skin care applications, though specific uses vary widely across different traditions. Scientific evidence suggests that Hamamelis extracts from the leaf and bark of *Hamamelis virginiana* demonstrate strong antioxidant and anti-inflammatory effects, with the bark extract also showing potential to inhibit collagenase and elastase. However, topically applied breast milk has been shown to be more effective in treating diaper dermatitis than a Hamamelis cream, though this finding may be influenced by baseline severity differences. The structural diversity of proteins from *Hamamelis aphids* indicates they target various plant processes but no specific traditional uses are recorded for the plant itself. There is currently no reported major safety issues or known drug interactions associated with Hamamelis use.
- Best evidence
- B
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study found that bicycle proteins from Hamamelis aphids exhibit saposin-like folds, with structural diversity suggesting they target various plant processes.
- The assessment identified two EU regulated pests (Phytophthora ramorum non-EU isolates and Scirtothrips dorsalis) as potentially associated with Hamamelis mollis plants from the UK.
- Both Hamamelis virginiana leaf and bark extracts showed strong antioxidant and anti-inflammatory effects, with the bark extract additionally inhibiting collagenase and elastase.
- Rodent predation on Hamamelis japonica galls shifted with the relative frequency of two aphid species, influenced by predator learning and gall structural complexity.
- Topically applied breast milk showed greater improvement in diaper dermatitis compared to a Hamamelis virginiana cream, though baseline severity differences were noted.
Frequently asked questions
What is Witch-hazel?
Witch-hazel (Hamamelis) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Witch-hazel?
5 sourced findings are recorded for Witch-hazel; the strongest carries evidence grade B. For example: The study found that bicycle proteins from Hamamelis aphids exhibit saposin-like folds, with structural diversity suggesting they target various plant processes.
How strong is the evidence for Witch-hazel?
The strongest finding for Witch-hazel carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Witch-hazel safe? What are the side effects?
No major safety issues are recorded for Witch-hazel in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Witch-hazel interact with medications?
No drug interactions are recorded for Witch-hazel in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Witch-hazel?
Witch-hazel is also known as: гамамелис, Hamamélis.
Is Witch-hazel a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Comparative Analysis of Polyphenol-Rich Extracts from Hamamelis virginiana Leaves and Bark: ROS Scavenging and Anti-Inflammatory Effects on Skin Cells. literature abstract metadata
- T2 Comparison of the Effects of Breast Milk and Hamamelis virginiana (Witch Hazel) on the Healing of Diaper Dermatitis in Infants: A Randomized Trial. literature abstract metadata
- T2 Associational effects of closely related insect galls on rodent predators mediated by predator learning. literature abstract metadata
- T2 Commodity risk assessment of Hamamelis mollis plants from the UK. literature abstract metadata
- T2 Rapidly evolving aphid gall effector proteins exhibit saposin-like folds. literature abstract metadata