Sweet-scented Hellebore
Helleborus odorus
Helleborus odorus is a perennial flowering plant native to southern Europe. While its traditional medicinal uses are not well-documented, studies have identified several biologically active compounds such as alkaloids and phenols, which show potential for various diseases. Deglucohellebrin from Helleborus odorus demonstrated anti-glioma activity in cell lines; however, further research is needed to confirm these findings. Additionally, root extracts of Helleborus odorus subsp. cyclophyllus exhibited antioxidant properties and induced cytotoxic effects in bacterial and mammalian cells. The sepals of Helleborus odorus and H. niger also showed variations in pigment contents and optical properties across developmental phases, contributing to their ecological roles. No major safety issues or recorded drug interactions have been reported for this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Sepals of Helleborus odorus and H. niger showed differences in pigment contents and optical properties across developmental phases.
- The study found that deglucohellebrin from Helleborus odorus showed anti-glioma activity in cell lines, though further research is needed.
- The root methanolic extract of Helleborus odorus subsp. cyclophyllus showed antiseizure activity mainly due to new compounds (2) and hellebrin (4).
- Helleborus odorus subsp. cyclophyllus root extracts showed antioxidant properties and induced cytotoxic effects in bacterial and mammalian cells.
- The study identified alkaloids and phenols as potentially active compounds in Helleborus odorus, showing affinity for carbonic anhydrases.
Frequently asked questions
What is Sweet-scented Hellebore?
Sweet-scented Hellebore (Helleborus odorus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Sweet-scented Hellebore?
5 sourced findings are recorded for Sweet-scented Hellebore; the strongest carries evidence grade D. For example: Sepals of Helleborus odorus and H. niger showed differences in pigment contents and optical properties across developmental phases.
How strong is the evidence for Sweet-scented Hellebore?
The strongest finding for Sweet-scented Hellebore carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Sweet-scented Hellebore safe? What are the side effects?
No major safety issues are recorded for Sweet-scented Hellebore in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Sweet-scented Hellebore interact with medications?
No drug interactions are recorded for Sweet-scented Hellebore in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Sweet-scented Hellebore?
Sweet-scented Hellebore is also known as: Морозник душистый.
Is Sweet-scented Hellebore a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Deglucohellebrin: A Potent Agent for Glioblastoma Treatment. literature abstract metadata
- T2 Antiseizure potential of the ancient Greek medicinal plant Helleborus odorus subsp. cyclophyllus and identification of its main active principles. literature abstract metadata
- T2 Comparative Study of Temporal Changes in Pigments and Optical Properties in Sepals of Helleborus odorus and H. niger from Prebloom to Seed Production. literature abstract metadata
- T2 Bioinformatics Tools for the Analysis of Active Compounds Identified in Ranunculaceae Species. literature abstract metadata
- T2 Helleborus odorus subsp. cyclophyllus: An Unexploited Source of Antioxidant, Antimicrobial, and Cytotoxic Bioactivity. literature abstract metadata