Willow-Leaved Water Croton
Homonoia riparia
Homonoia riparia is a plant traditionally used by the Miao people in Hainan, China. While specific traditional uses are not well-documented, scientific evidence suggests that extracts and fractions of this plant exhibit significant nephroprotective activity against cisplatin-induced toxicity. Additionally, Homonoia riparia and its major component, myricitrin, have been shown to inhibit high glucose-induced apoptosis and ROS generation in human retinal pericytes, indicating potential benefits for ocular health. In vitro studies also indicate that riparsaponin, a compound found in the plant, can induce apoptosis in human oral carcinoma cells by altering protein expression involved in apoptosis and cell adhesion. No major safety concerns or recorded drug interactions have been identified to date, but further research is needed to fully understand its potential applications and limitations.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The extracts and fractions of Homonoia riparia showed significant nephroprotective activity against cisplatin-induced toxicity.
- Homonoia riparia and its major component, myricitrin, inhibit high glucose-induced apoptosis and ROS generation in human retinal pericytes.
- Homonoia riparia is one of several plants documented for their medicinal value in this ethnobotanical study of Miao traditional medicine in Hainan, China.
- Riparsaponin induced apoptosis in human oral carcinoma cells, altering expression of several proteins involved in apoptosis and cell adhesion.
Frequently asked questions
What is Willow-Leaved Water Croton?
Willow-Leaved Water Croton (Homonoia riparia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Willow-Leaved Water Croton?
4 sourced findings are recorded for Willow-Leaved Water Croton; the strongest carries evidence grade D. For example: The extracts and fractions of Homonoia riparia showed significant nephroprotective activity against cisplatin-induced toxicity.
How strong is the evidence for Willow-Leaved Water Croton?
The strongest finding for Willow-Leaved Water Croton carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Willow-Leaved Water Croton safe? What are the side effects?
No major safety issues are recorded for Willow-Leaved Water Croton in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Willow-Leaved Water Croton interact with medications?
No drug interactions are recorded for Willow-Leaved Water Croton in our sources. This does not rule them out — check with a pharmacist.
Is Willow-Leaved Water Croton a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Antioxidant and Nephroprotective Activities of the Extract and Fractions of Homonoia riparia Lour. literature abstract metadata
- T2 Homonoia riparia and its major component, myricitrin, inhibit high glucose-induced apoptosis of human retinal pericytes. literature abstract metadata
- T2 Riparsaponin isolated from Homonoia riparia Lour induces apoptosis of oral cancer cells. literature abstract metadata
- T2 Ethnobotanical study of traditional medicinal plants used by the Miao people in Hainan, China. literature abstract metadata