Horsfieldia irya
Horsfieldia irya
Horsfieldia irya is a plant native to Southeast Asia, particularly in areas surrounding Tasik Kenyir. While traditional uses of this plant are not documented, it has shown promise in scientific research. Compounds from Horsfieldia species have demonstrated moderate cytotoxicity against cancer cell lines and significant antifungal activity against Fusarium culmorum by targeting ergosterol biosynthesis. Myristicyclins A and B isolated from a related species, Horsfieldia spicata, exhibited in vitro antimalarial activity against Plasmodium falciparum. After 34 years of observation, 90 species of riparian plants were recorded near Tasik Kenyir streams, including Horsfieldia irya. No major safety concerns or drug interactions have been reported for this plant to date.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Compound 13 from Horsfieldia irya showed moderate cytotoxicity against cancer cell lines with less activity against normal cells.
- The study found that a nutmeg extract showed significant activity against several phytopathogenic fungi, particularly Fusarium culmorum, through targeting ergosterol biosynthesis.
- After 34 years, 90 species of riparian plants were recorded across four streams near Tasik Kenyir.
- Myristicyclins A and B, isolated from Horsfieldia spicata, showed antimalarial activity against Plasmodium falciparum in vitro.
Frequently asked questions
What is Horsfieldia irya?
Horsfieldia irya (Horsfieldia irya) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Horsfieldia irya?
4 sourced findings are recorded for Horsfieldia irya; the strongest carries evidence grade D. For example: Compound 13 from Horsfieldia irya showed moderate cytotoxicity against cancer cell lines with less activity against normal cells.
How strong is the evidence for Horsfieldia irya?
The strongest finding for Horsfieldia irya carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Horsfieldia irya safe? What are the side effects?
No major safety issues are recorded for Horsfieldia irya in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Horsfieldia irya interact with medications?
No drug interactions are recorded for Horsfieldia irya in our sources. This does not rule them out — check with a pharmacist.
Is Horsfieldia irya a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Myristicyclins A and B: antimalarial procyanidins from Horsfieldia spicata from Papua New Guinea. literature abstract metadata
- T2 Species richness of riparian vegetation after three decades of Kenyir dam establishment. literature abstract metadata
- T2 Cytotoxicity of acylphloroglucinol derivatives from the fruits of Horsfieldia irya. literature abstract metadata
- T2 Phytoconstituents and Ergosterol Biosynthesis-Targeting Antimicrobial Activity of Nutmeg (Myristica fragans Houtt.) against Phytopathogens. literature abstract metadata