Alaska iris
Iris setosa
Iris setosa is a plant native to Japan and China. Traditionally, its use has not been documented in any known medical practices or folk remedies. Scientifically, an xanthone O-glucoside from Iris setosa demonstrated promising anti-amoebic activity against Naegleria fowleri with minimal cytotoxicity, indicating potential for amoebic infections. Additionally, the plant extract showed selective amoebicidal activity against Acanthamoeba while being relatively non-toxic to human corneal cells. While the reproductive success of Iris setosa is influenced by specific floral features and pollinator visits, its physiological dormancy characteristics are noted with non-deep PD being predominant among tested species. No significant safety concerns or drug interactions have been recorded for this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- A xanthone O-glucoside from Iris setosa showed promising anti-amoebic activity against Naegleria fowleri with negligible cytotoxicity.
- Iris setosa extract showed selective amoebicidal activity against Acanthamoeba with low toxicity to human corneal cells.
- Iris setosa's reproductive success depends on specific floral features and pollinator visits, with outcrossing being the main breeding system.
- Iris setosa showed physiological dormancy, with non-deep PD being the dominant type among tested species.
Frequently asked questions
What is Alaska iris?
Alaska iris (Iris setosa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Alaska iris?
4 sourced findings are recorded for Alaska iris; the strongest carries evidence grade D. For example: A xanthone O-glucoside from Iris setosa showed promising anti-amoebic activity against Naegleria fowleri with negligible cytotoxicity.
How strong is the evidence for Alaska iris?
The strongest finding for Alaska iris carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Alaska iris safe? What are the side effects?
No major safety issues are recorded for Alaska iris in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Alaska iris interact with medications?
No drug interactions are recorded for Alaska iris in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Alaska iris?
Alaska iris is also known as: Ирис щетинистый, iris d'Alaska.
Is Alaska iris a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Seed dormancy types and germination response of 15 plant species in temperate montane peatlands. literature abstract metadata
- T2 Iris setosa Pall. ex Link Extract Reveals Amoebicidal Activity against Acanthamoeba castellanii and Acanthamoeba polyphaga with Low Toxicity to Human Corneal Cells. literature abstract metadata
- T2 Effects of Floral Characters on the Pollination Biology and Breeding System of Iris setosa (Iridaceae): A Cold-Tolerant Ornamental Species from Jilin Province. literature abstract metadata
- T2 A xanthone O-glucoside isolated from Iris setosa Pall. ex Link exhibits promising anti-amoebic activity against the brain-eating amoeba Naegleria fowleri. literature abstract metadata