Alaska iris
Iris setosa
Iris setosa is a flowering plant native to Japan and Korea. Traditional uses of this plant are not well-documented, with no specific recorded practices or applications in any traditional medicine systems. Scientific evidence suggests that an xanthone O-glucoside from Iris setosa exhibits promising anti-amoebic activity against Naegleria fowleri, showing negligible cytotoxicity. Additionally, the extract demonstrates selective amoebicidal activity against Acanthamoeba with low toxicity to human corneal cells. While these findings are encouraging, more research is needed to confirm and expand upon them. Safety concerns for Iris setosa appear minimal, with no major issues recorded. There are also no known drug interactions reported for this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- A xanthone O-glucoside from Iris setosa showed promising anti-amoebic activity against Naegleria fowleri with negligible cytotoxicity.
- Iris setosa extract showed selective amoebicidal activity against Acanthamoeba with low toxicity to human corneal cells.
- Iris setosa's reproductive success depends on specific floral features and pollinator visits, with outcrossing being the main breeding system.
- Iris setosa showed physiological dormancy, with non-deep PD being the dominant type among tested species.
Frequently asked questions
What is Alaska iris?
Alaska iris (Iris setosa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Alaska iris?
4 sourced findings are recorded for Alaska iris; the strongest carries evidence grade D. For example: A xanthone O-glucoside from Iris setosa showed promising anti-amoebic activity against Naegleria fowleri with negligible cytotoxicity.
How strong is the evidence for Alaska iris?
The strongest finding for Alaska iris carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Alaska iris safe? What are the side effects?
No major safety issues are recorded for Alaska iris in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Alaska iris interact with medications?
No drug interactions are recorded for Alaska iris in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Alaska iris?
Alaska iris is also known as: Ирис щетинистый, iris d'Alaska.
Is Alaska iris a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Seed dormancy types and germination response of 15 plant species in temperate montane peatlands. literature abstract metadata
- T2 Iris setosa Pall. ex Link Extract Reveals Amoebicidal Activity against Acanthamoeba castellanii and Acanthamoeba polyphaga with Low Toxicity to Human Corneal Cells. literature abstract metadata
- T2 Effects of Floral Characters on the Pollination Biology and Breeding System of Iris setosa (Iridaceae): A Cold-Tolerant Ornamental Species from Jilin Province. literature abstract metadata
- T2 A xanthone O-glucoside isolated from Iris setosa Pall. ex Link exhibits promising anti-amoebic activity against the brain-eating amoeba Naegleria fowleri. literature abstract metadata