slender-leaf iris

Iris tenuifolia

Iris tenuifolia is a traditional plant primarily found in Iran. While its use in traditional medicine has not been extensively documented, studies have shown promising results. In mice models, extracts of Iris tenuifolia significantly reduced brain damage when administered 1 hour before or immediately after induced ischemia, but had no effect when given 4 hours later. The flavonoids from this plant demonstrated a survival-promoting effect on cortical neurons under oxidative stress and showed potential antioxidant and α-glucosidase inhibitory activities. Additionally, five new flavonoids were identified, with one showing potential antibacterial activity and others demonstrating activity against leukemia cells. No major safety issues or drug interactions have been recorded to date.

At a glance
Best evidence
D
Cautions

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • IT flavonoids showed a survival-promoting effect on cortical neurons under oxidative stress, partly through ERK and PI3K/Akt pathways involving Shp2. D PMID
  • Iris tenuifolia extract reduced brain damage significantly when administered 1 hour before or immediately after induced ischemia in mice, but had no effect when given 4 hours later. D PMID
  • Five new flavonoids from Iris tenuifolia showed potential antioxidant and α-glucosidase inhibitory activities. D PMID
  • The study identified several new compounds from Iris tenuifolia, with one showing potential antibacterial activity and others demonstrating activity against leukemia cells. D PMID

Frequently asked questions

What is slender-leaf iris?

slender-leaf iris (Iris tenuifolia) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about slender-leaf iris?

4 sourced findings are recorded for slender-leaf iris; the strongest carries evidence grade D. For example: IT flavonoids showed a survival-promoting effect on cortical neurons under oxidative stress, partly through ERK and PI3K/Akt pathways involving Shp2.

How strong is the evidence for slender-leaf iris?

The strongest finding for slender-leaf iris carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is slender-leaf iris safe? What are the side effects?

No major safety issues are recorded for slender-leaf iris in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does slender-leaf iris interact with medications?

No drug interactions are recorded for slender-leaf iris in our sources. This does not rule them out — check with a pharmacist.

What are the common names of slender-leaf iris?

slender-leaf iris is also known as: Ирис тонколистный.

Is slender-leaf iris a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 Phosphatase-mediated intracellular signaling contributes to neuroprotection by flavonoids of Iris tenuifolia. literature abstract metadata
  2. T2 Ethanol Iris tenuifolia extract reduces brain damage in a mouse model of cerebral ischaemia. literature abstract metadata
  3. T2 Chromane Derivatives from Underground Parts of Iris tenuifolia and Their In Vitro Antimicrobial, Cytotoxicity and Antiproliferative Evaluation. literature abstract metadata
  4. T2 Five new flavonoids and their pharmacological activities from Iris tenuifolia Pall. literature abstract metadata