Jatropha integerrima
Jatropha integerrima
Jatropha integerrima, a plant native to tropical regions of Asia and Africa, has not been extensively used in traditional medicine. However, scientific research indicates potential anticonvulsant properties, with ethanolic extracts showing activity comparable to diazepam in mouse models. Additionally, studies suggest that compounds from Jatropha integerrima may have cytoprotective effects against certain viruses and favorable interactions with SARS-CoV-2 targets, though direct viral efficacy is yet to be confirmed. The plant also demonstrates potential benefits for diabetes management, as MEJI extracts showed dose-dependent reductions in blood glucose levels and improved lipid profiles in diabetic rats. Furthermore, tannins from the flowers exhibited potent antimicrobial and antibiofilm activity against multidrug-resistant Klebsiella pneumoniae by downregulating biofilm-related genes. No significant safety concerns or recorded drug interactions have been noted for Jatropha integerrima.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Ethanolic extracts of Jatropha integerrima, particularly the petroleum ether fraction, showed significant anticonvulsant activity in mice models, comparable to diazepam.
- Vitexin and isovitexin from Jatropha integerrima showed variable cytoprotective effects against certain viruses in vitro and favorable molecular interactions with SARS-CoV-2 targets, though direct viral efficacy remains unconfirmed.
- MEJI showed dose-dependent reductions in blood glucose, favorable modulation of lipid profile, and improved antioxidant enzyme activities in STZ-induced diabetic rats.
- Two tannins from Jatropha integerrima flowers showed potent antimicrobial and antibiofilm activity against multidrug-resistant Klebsiella pneumoniae by downregulating biofilm-related genes.
Frequently asked questions
What is Jatropha integerrima?
Jatropha integerrima (Jatropha integerrima) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Jatropha integerrima?
4 sourced findings are recorded for Jatropha integerrima; the strongest carries evidence grade D. For example: Ethanolic extracts of Jatropha integerrima, particularly the petroleum ether fraction, showed significant anticonvulsant activity in mice models, comparable to diazepam.
How strong is the evidence for Jatropha integerrima?
The strongest finding for Jatropha integerrima carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Jatropha integerrima safe? What are the side effects?
No major safety issues are recorded for Jatropha integerrima in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Jatropha integerrima interact with medications?
No drug interactions are recorded for Jatropha integerrima in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Jatropha integerrima?
Jatropha integerrima is also known as: Ятрофа цельнокрайняя.
Is Jatropha integerrima a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 The gene-modulating power of Tannins isolated from Jatropha integerrima flowers on the transcriptomic profile of multidrug-resistant Klebsiella pneumoniae. literature abstract metadata
- T2 Unraveling the Antioxidant, Antihyperlipidemic, and Antidiabetic Potential of Jatropha integerrima in Streptozotocin-Induced Diabetic Rats. literature abstract metadata
- T2 Broad-spectrum antiviral potential of vitexin and isovitexin from Jatropha integerrima: in vitro cytoprotective effects and in silico insights. literature abstract metadata
- T2 Antiepileptic potential of Jatropha integerrima Jacq. extracts: an exploratory study integrating in vivo seizure models and computational analysis. literature abstract metadata