Red-fruit Spicebush
Lindera erythrocarpa
Lindera erythrocarpa, also known as Chinese spicebush or red-flowered sweetshrub, is a plant native to East Asia. While it has not been traditionally used in any specific medical practices, studies have shown promising results in its potential benefits. Dihydropashanone isolated from the plant protected mouse hippocampus HT22 cells from glutamate-induced cell death, suggesting possible neuroprotective properties. Additionally, ML (the extract) reduced airway inflammation by inhibiting TAK1 activity in human bronchial epithelial cells and showed significant reduction in blood pressure in spontaneously hypertensive rats, indicating potential anti-inflammatory and antihypertensive effects. However, the scientific evidence is currently limited to these observations, and more research is needed to confirm these findings. No major safety issues or drug interactions have been reported for Lindera erythrocarpa; however, further studies are recommended before extensive use can be advised.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Dihydropashanone isolated from Lindera erythrocarpa protected mouse hippocampus HT22 cells from glutamate-induced cell death.
- ML reduces airway inflammation by inhibiting TAK1 activity in human bronchial epithelial cells.
- Unique nine oligomeric flavonoids from Lindera erythrocarpa roots inhibit autophagy by blocking its fusion process in cells.
- Lindera erythrocarpa leaf ethanolic extract showed a significant reduction in blood pressure in spontaneously hypertensive rats.
Frequently asked questions
What is Red-fruit Spicebush?
Red-fruit Spicebush (Lindera erythrocarpa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Red-fruit Spicebush?
4 sourced findings are recorded for Red-fruit Spicebush; the strongest carries evidence grade D. For example: Dihydropashanone isolated from Lindera erythrocarpa protected mouse hippocampus HT22 cells from glutamate-induced cell death.
How strong is the evidence for Red-fruit Spicebush?
The strongest finding for Red-fruit Spicebush carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Red-fruit Spicebush safe? What are the side effects?
No major safety issues are recorded for Red-fruit Spicebush in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Red-fruit Spicebush interact with medications?
No drug interactions are recorded for Red-fruit Spicebush in our sources. This does not rule them out — check with a pharmacist.
Is Red-fruit Spicebush a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Linderanidins A-F: Rare oligomeric flavonoids with an unusual C-3-C-4 linkage from the roots of Lindera erythrocarpa and their inhibitory activities on autophagy. literature abstract metadata
- T2 Methyl lucidone inhibits airway inflammatory response by reducing TAK1 activity in human bronchial epithelial NCI-H292 cells. literature abstract metadata
- T2 Dihydropashanone Isolated from Lindera erythrocarpa, a Potential Natural Product for the Treatment of Neurodegenerative Diseases. literature abstract metadata
- T2 Antihypertensive Effects of Lindera erythrocarpa Makino via NO/cGMP Pathway and Ca2+ and K+ Channels. literature abstract metadata