Chinese Honeysuckle
Lonicera japonica
Lonicera japonica, commonly known as Japanese Honeysuckle, is a traditional plant used in East Asian medicine. While its specific uses are not well-documented, it has been studied for various potential health benefits. Scientific evidence suggests that compounds from Lonicera japonica, such as caffeoylquinic acids and rhoifolin, may have anti-diabetic properties by enhancing glucose uptake and upregulating browning markers in adipocytes. Additionally, Qishen paste derived from this plant has shown promise in improving cardiac function and conduction in heart failure mice through the regulation of Cx43 in cardiac resident macrophages. However, these findings are preliminary and require further research to confirm their clinical significance. No significant safety concerns or drug interactions have been reported for Lonicera japonica; however, as with any herbal supplement, it is advisable to consult a healthcare provider before use.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Six caffeoylquinic acids were isolated from Lonicera japonica and showed selective α-glucosidase inhibition and enhanced glucose uptake.
- Both catalpol and rhoifolin from Lonicera japonica upregulated browning markers and thermogenic genes in adipocytes via β3-AR signaling.
- Qishen paste improved cardiac function and conduction in heart failure mice by upregulating Cx43 in cardiac resident macrophages.
- The study identified a new compound, 16,17-dihydro-ophiobolin X, from an endophyte of Lonicera japonica, which showed moderate cytotoxic activity against certain cell lines.
- A high-performance photoelectrochemical sensor based on in situ grown ZnIn2S4@ZnWO4 heterojunctions was developed for sensitive chlorogenic acid detection, showing good linear relationships and low detection limits.
- The study found that rbcL and trnH-psbA markers provided reliable species identification and phylogenetic resolution for endemic plant species in the western Himalayas.
Frequently asked questions
What is Chinese Honeysuckle?
Chinese Honeysuckle (Lonicera japonica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Chinese Honeysuckle?
6 sourced findings are recorded for Chinese Honeysuckle; the strongest carries evidence grade D. For example: Six caffeoylquinic acids were isolated from Lonicera japonica and showed selective α-glucosidase inhibition and enhanced glucose uptake.
How strong is the evidence for Chinese Honeysuckle?
The strongest finding for Chinese Honeysuckle carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Chinese Honeysuckle safe? What are the side effects?
No major safety issues are recorded for Chinese Honeysuckle in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Chinese Honeysuckle interact with medications?
No drug interactions are recorded for Chinese Honeysuckle in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Chinese Honeysuckle?
Chinese Honeysuckle is also known as: Chevrefeuille du Japon.
Is Chinese Honeysuckle a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Fat Browning Effects of Catalpol and Rhoifolin from Rehmannia glutinosa (Gaertn.) and Lonicera japonica (Thunb.) in 3T3-L1 Adipocytes via the β3-AR Signaling Pathway. literature abstract metadata
- T2 Caffeoylquinic Acids From Lonicera japonica Thunb. as Hypoglycemic Agents: Network Pharmacology and Pharmacological Validation. literature abstract metadata
- T2 16,17-Dihydro-ophiobolin X: a novel cytotoxic sesterterpenoid from the endophyte Penicillium ochrochloron YT2022-65. literature abstract metadata
- T2 In Situ Grown ZnIn2S4@ZnWO4 Heterojunction for Highly Sensitive Photoelectrochemical Detection of Chlorogenic Acid. literature abstract metadata
- T2 Qishen Paste Improves Cardiac Conduction in Heart Failure by Regulating Cardiac Resident Macrophage Connexin43. literature abstract metadata
- T2 DNA barcoding and phylogenetic insights into the selected endemic flora of the Western Himalayas. literature abstract metadata