Lycoris radiata
Lycoris radiata
Lycoris radiata, commonly known as the naked lady or magic lily, is a flowering plant native to East Asia. While it has significant cultural and ornamental value in traditional practices, there are no documented historical uses of Lycoris radiata for medicinal purposes. Scientific studies have provided insights into its biological mechanisms. Research indicates that Lycorine, one of its active compounds, can induce ferroptosis in colorectal cancer cells by inhibiting Nrf2 signaling and reducing SLC7A11 levels. Additionally, the plant's galanthamine biosynthesis pathway has been studied, revealing evolutionary aspects of Amaryllidaceae alkaloids. Phylogenetic analyses have also shed light on its genetic structure. Safety profiles for Lycoris radiata appear to be favorable with no major issues recorded. There are currently no known drug interactions associated with this plant, though further research is ongoing to fully understand its potential effects and applications.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study provided insights into the galanthamine biosynthesis pathway in Lycoris radiata and revealed the evolutionary origin of Amaryllidaceae alkaloids.
- The study identifies a novel LncRNA401-LrWRKY70 regulatory module that influences blue-purple flower color formation in Lycoris through metabolic reprogramming.
- Lycorine induces ferroptosis in colorectal cancer cells by suppressing DPP3-mediated Nrf2 signaling and reducing SLC7A11 levels.
- Phylogenetic analyses based on chloroplast and nuclear ribosomal ITS sequences revealed differences in the placement of Lycoris chunxiaoensis, suggesting cytonuclear discordance.
Frequently asked questions
What is Lycoris radiata?
Lycoris radiata (Lycoris radiata) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Lycoris radiata?
4 sourced findings are recorded for Lycoris radiata; the strongest carries evidence grade D. For example: The study provided insights into the galanthamine biosynthesis pathway in Lycoris radiata and revealed the evolutionary origin of Amaryllidaceae alkaloids.
How strong is the evidence for Lycoris radiata?
The strongest finding for Lycoris radiata carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Lycoris radiata safe? What are the side effects?
No major safety issues are recorded for Lycoris radiata in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Lycoris radiata interact with medications?
No drug interactions are recorded for Lycoris radiata in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Lycoris radiata?
Lycoris radiata is also known as: Ликорис лучистый.
Is Lycoris radiata a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Lycorine suppresses DPP3-mediated Nrf2 signaling, thereby reducing SLC7A11 levels to trigger ferroptosis in colorectal cancer cells. literature abstract metadata
- T2 The LncRNA401-LrWRKY70 Module Regulates the Blue-Purple Flower Color Formation in Lycoris. literature abstract metadata
- T2 Chloroplast genomics and nuclear ribosomal ITS phylogeny reveal pronounced cytonuclear discordance in Lycoris chunxiaoensis. literature abstract metadata
- T2 A chromosome-level genome assembly of Lycoris radiata unveils evolutionary origin of Amaryllidaceae alkaloids and elucidates the complete pathway of galanthamine biosynthesis. literature abstract metadata