Mahonia japonica
Mahonia japonica
Mahonia japonica is a plant traditionally used in East Asian medicine but lacks specific recorded traditional uses. Scientific evidence suggests that its compound isotetrandrine can block NMO-IgG binding to AQP4 without affecting AQP4 function, indicating potential therapeutic applications for neuromyelitis optica (NMO). However, the strength of this evidence is limited by the current scope of research. The plant's female Drosophila suzukii behavior and chemical properties related to volatile emissions are not directly linked to its traditional or potential medicinal uses. Safety concerns do not appear to be significant based on available data, and there are no recorded drug interactions associated with Mahonia japonica.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Isotetrandrine from Mahonia japonica can block NMO-IgG binding to AQP4 without affecting AQP4 function.
- Females of Drosophila suzukii prioritized thermally optimal oviposition sites over nutritionally favorable ones, even when temperatures were suboptimal.
- Mahonia japonica emitted more floral volatiles during daylight than at night, with maximum rates occurring in the middle of the light period.
- Mutations and deletions affecting the 9-epi-caryophyllene synthase enzyme activity were identified, enhancing understanding of its function.
Frequently asked questions
What is Mahonia japonica?
Mahonia japonica (Mahonia japonica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Mahonia japonica?
4 sourced findings are recorded for Mahonia japonica; the strongest carries evidence grade D. For example: Isotetrandrine from Mahonia japonica can block NMO-IgG binding to AQP4 without affecting AQP4 function.
How strong is the evidence for Mahonia japonica?
The strongest finding for Mahonia japonica carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Mahonia japonica safe? What are the side effects?
No major safety issues are recorded for Mahonia japonica in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Mahonia japonica interact with medications?
No drug interactions are recorded for Mahonia japonica in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Mahonia japonica?
Mahonia japonica is also known as: Магония японская, Mahonia du Japon.
Is Mahonia japonica a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Emission of floral volatiles from Mahonia japonica (Berberidaceae). literature abstract metadata
- T2 Isotetrandrine Reduces Astrocyte Cytotoxicity in Neuromyelitis Optica by Blocking the Binding of NMO-IgG to Aquaporin 4. literature abstract metadata
- T2 Study on the Functional Characterization of 9‑epi-Caryophyllene Synthase from Lavandula x intermedia (Lavandin). literature abstract metadata
- T2 Temperature overrides nutritional cues for optimal oviposition decision in a polyphagous invasive insect. literature abstract metadata