Maytenus gonoclados
Maytenus robusta
Maytenus robusta is a traditional medicine plant native to South America. While its use in local traditions has not been extensively documented, studies have shown promising effects of Maytenus robusta extract on colon inflammation and liver function. In mice with DSS-induced colitis, the extract demonstrated ameliorative effects. Additionally, compounds derived from this plant exhibited variable cytotoxic activity against various cancer cell lines and reduced liver damage in CCl4-induced hepatotoxicity models, possibly due to its antioxidant properties. The concentration of terpenoids in Maytenus robusta varies by season and part of the plant, with certain compounds being more abundant at specific times. Safety concerns are currently minimal, as no major issues have been recorded. There is also no reported evidence of drug interactions associated with this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Maytenus robusta extract showed ameliorative effects on colon inflammation and liver function in mice with DSS-induced colitis.
- Compounds derived from Maytenus robusta showed variable cytotoxic activity against different cancer cell lines.
- Maytenus robusta extract reduced liver damage and normalized enzyme levels in CCl4-induced hepatotoxicity in mice and HepG2 cells, likely due to its antioxidant properties.
- The concentrations of terpenoids in Maytenus robusta vary by season and plant part, with highest levels of certain compounds found in specific times of the year.
Frequently asked questions
What is Maytenus gonoclados?
Maytenus gonoclados (Maytenus robusta) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Maytenus gonoclados?
4 sourced findings are recorded for Maytenus gonoclados; the strongest carries evidence grade D. For example: Maytenus robusta extract showed ameliorative effects on colon inflammation and liver function in mice with DSS-induced colitis.
How strong is the evidence for Maytenus gonoclados?
The strongest finding for Maytenus gonoclados carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Maytenus gonoclados safe? What are the side effects?
No major safety issues are recorded for Maytenus gonoclados in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Maytenus gonoclados interact with medications?
No drug interactions are recorded for Maytenus gonoclados in our sources. This does not rule them out — check with a pharmacist.
Is Maytenus gonoclados a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Seasonal variation of gastroprotective terpenoids in Maytenus robusta (Celastraceae) quantified by gas chromatography-flame ionization detection (GC-FID). literature abstract metadata
- T2 Hepatoprotective effect of Maytenus robusta Reiss extract on CCl4-induced hepatotoxicity in mice and HepG2 cells. literature abstract metadata
- T2 Imines and lactones derived from friedelanes and their cytotoxic activity. literature abstract metadata
- T2 Maytenus robusta Reissek, a medicinal plant popularly used to treat digestive diseases, promotes ameliorative effects in colon and liver of mice exposed to dextran sulfate sodium. literature abstract metadata