Mirabilis jalapa
Mirabilis jalapa
Mirabilis jalapa, commonly known as four-o'clock or angel's trumpet, is a flowering plant traditionally used in various cultural practices but lacks specific documented traditional medicinal uses. Scientific research has shown that extracts from Mirabilis jalapa and Acalypha wilkesiana exhibit synergistic antimicrobial activity against Staphylococcus aureus and Pseudomonas aeruginosa, indicating potential antibacterial properties. Additionally, studies have explored the molecular mechanisms behind corolla movement in this plant, revealing involvement of hormonal pathways, Ca2+-ROS signaling, and WRKY-mediated transcriptional regulation. The crystal structure of ribosome-inactivating protein (MAP) from Mirabilis jalapa has also been determined, showing it binds to both eukaryotic and E. coli ribosomes, potentially indicating further biological activity. To date, no major safety issues or drug interactions have been recorded for this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The study found that ethanol and aqueous extracts of Acalypha wilkesiana and Mirabilis jalapa showed synergistic antimicrobial activity against Staphylococcus aureus and Pseudomonas aeruginosa.
- The study found that corolla movement in Mirabilis jalapa involves hormonal pathways, Ca2+-ROS signaling, and WRKY-mediated transcriptional regulation.
- The study determined the crystal structure of Mirabilis jalapa's ribosome-inactivating protein (MAP) and found it binds to both eukaryotic and E. coli ribosomes.
- Strain MIRK71, an endophytic Streptomyces species from Mirabilis jalapa, exhibited strong antimicrobial activity against multidrug-resistant pathogens.
- MirMAN-mediated mannose promotes Arabidopsis root development by enhancing auxin-related gene expression and regulating BR signaling via MYB41-DWF4.
Frequently asked questions
What is Mirabilis jalapa?
Mirabilis jalapa (Mirabilis jalapa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Mirabilis jalapa?
5 sourced findings are recorded for Mirabilis jalapa; the strongest carries evidence grade D. For example: The study found that ethanol and aqueous extracts of Acalypha wilkesiana and Mirabilis jalapa showed synergistic antimicrobial activity against Staphylococcus aureus and Pseudomonas aeruginosa.
How strong is the evidence for Mirabilis jalapa?
The strongest finding for Mirabilis jalapa carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Mirabilis jalapa safe? What are the side effects?
No major safety issues are recorded for Mirabilis jalapa in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Mirabilis jalapa interact with medications?
No drug interactions are recorded for Mirabilis jalapa in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Mirabilis jalapa?
Mirabilis jalapa is also known as: Ночная красавица.
Is Mirabilis jalapa a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Antibacterial potential and chromatographic profiling of bioactive compounds from endophytic Streptomyces sp. strain MIRK71 isolated from Mirabilis jalapa (L.). literature abstract metadata
- T2 Structure of Ribosome-Inactivating Protein from Mirabilis jalapa and Its L12-Stalk-Dependent Inhibition of Escherichia coli Ribosome. literature abstract metadata
- T2 Transcriptome Analysis Revealed Potential Regulatory Networks Underlying Corolla Movement in Mirabilis jalapa (Nyctaginaceae). literature abstract metadata
- T2 MirMAN-mediated mannose promotes root development in Arabidopsis via the MYB41-DWF4 module regulating brassinosteroid signaling pathways. literature abstract metadata
- T2 Synergistic and multi-targeting efficacy of Acalypha wilkesiana and Mirabilis jalapa: an integrated in-vitro and in-silico investigation against Staphylococcus aureus and Pseudomonas aeruginosa. literature abstract metadata