Nutmeg
Myristica
Myristica, commonly known as nutmeg, originates from traditional medicine practices in Southeast Asia. Traditionally, it has been used in culinary and aromatic applications but specific medicinal uses are not well-documented. Scientific evidence suggests that Myristica fragrans contains lignans and terpenoids with potential pharmacological activities, particularly against Naegleria fowleri trophozoites, though further clinical investigation is needed to confirm these findings. Additionally, essential oils from Myristica fragrans have shown synergistic larvicidal activity against Aedes aegypti mosquitoes when combined with those of Plectranthus amboinicus. The plant's genome has been sequenced and analyzed, revealing its XY sex chromosome system and providing tools for seedling sexing, though this is not directly related to medicinal uses. No major safety issues or drug interactions have been recorded, making it generally safe when used appropriately.
- Best evidence
- A
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- All three malabaricone-conjugated silver nanoparticles showed potent activity against N. fowleri trophozoites, with Mal A-AgNPs demonstrating the highest potency.
- The study found that Myristica fragrans contains lignans and terpenoids with multiple pharmacological activities but requires further quality evaluation and clinical investigation.
- The study found that essential oils from Myristica fragrans and Plectranthus amboinicus showed synergistic larvicidal activity against Aedes aegypti mosquitoes.
- The study presents a haplotype-resolved nutmeg genome, identifying its XY sex chromosome system and developing a PCR-based marker for sexing seedlings.
Frequently asked questions
What is Nutmeg?
Nutmeg (Myristica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Nutmeg?
4 sourced findings are recorded for Nutmeg; the strongest carries evidence grade A. For example: All three malabaricone-conjugated silver nanoparticles showed potent activity against N. fowleri trophozoites, with Mal A-AgNPs demonstrating the highest potency.
How strong is the evidence for Nutmeg?
The strongest finding for Nutmeg carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Nutmeg safe? What are the side effects?
No major safety issues are recorded for Nutmeg in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Nutmeg interact with medications?
No drug interactions are recorded for Nutmeg in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Nutmeg?
Nutmeg is also known as: Мускатник, Muscadier.
Is Nutmeg a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Myristica fragrans: A comprehensive review of its botanical characterization, traditional uses, phytochemistry, and pharmacological properties. literature abstract metadata
- T2 A haplotype-resolved nutmeg genome reveals XY sex chromosome evolution and enables molecular sexing. literature abstract metadata
- T2 Development of an eco-friendly mosquito larvicide for dengue/chikungunya vector control. literature abstract metadata
- T2 Natural compound malabaricone conjugated with silver nanoparticle as an antiamoebic agent against primary Amoebic Meningoencephalitis (PAM) caused by Naegleria fowleri. literature abstract metadata