Apple Of Peru
Nicandra physalodes
Nicandra physalodes, commonly known as Physalis or golden pear, is a plant traditionally used in some folk medicine practices, particularly in South Asia and parts of Central America. While it has been utilized for various purposes such as treating skin conditions and digestive issues, no specific traditional uses are extensively documented. Scientifically, a chromosome-level genome assembly has been developed for this plant, which provides a valuable resource for genetic studies. Additionally, natural product extracts (NPE) from Nicandra physalodes have shown potential in improving acute lung injury by modulating immunometabolic pathways and inhibiting certain fungal species such as Fusarium spp., Aspergillus spp., and Penicillium spp. However, the evidence is limited and more research is needed to confirm these findings. To date, no significant safety concerns or drug interactions have been reported for Nicandra physalodes.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- NPGP gels with tea polyphenols showed improved structural and rheological properties, potentially useful as natural additives in the food industry.
- A chromosome-level genome assembly was generated for Nicandra physalodes, providing a foundation for studying its genetic traits.
- Seven fungal species were isolated from faba bean seeds, with Fusarium spp., Aspergillus spp., and Penicillium spp. being the most common, and Nicandra physalodes extracts showed variable inhibitory effects on fungal growth.
- NPE from Nicandra physalodes improved ALI in mice by remodeling immunometabolism and regulating the Leucine/PI3K/Akt/mTOR signaling pathway.
- The study characterized the chloroplast genome of Mandragora caulescens, showing it has a typical quadripartite structure and forms a close relationship with Nicandra physalodes.
Frequently asked questions
What is Apple Of Peru?
Apple Of Peru (Nicandra physalodes) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Apple Of Peru?
5 sourced findings are recorded for Apple Of Peru; the strongest carries evidence grade D. For example: NPGP gels with tea polyphenols showed improved structural and rheological properties, potentially useful as natural additives in the food industry.
How strong is the evidence for Apple Of Peru?
The strongest finding for Apple Of Peru carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Apple Of Peru safe? What are the side effects?
No major safety issues are recorded for Apple Of Peru in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Apple Of Peru interact with medications?
No drug interactions are recorded for Apple Of Peru in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Apple Of Peru?
Apple Of Peru is also known as: Nicandra physaloides.
Is Apple Of Peru a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Seedborne mycoflora of faba bean (Vicia fabae L.) and evaluation of plant extract and Trichoderma species against mycelium growth of selected fungi. literature abstract metadata
- T2 Characterization of the complete chloroplast genome of the rare medicinal plant: Mandragora caulescens (Solanaceae). literature abstract metadata
- T2 Gel properties of Nicandra physalodes (Linn.) gaertn. seeds polysaccharides with tea polyphenols and its application. literature abstract metadata
- T2 Multi-immunometabolomics mining: NP prevents hyperimmune in ALI by inhibiting Leucine/PI3K/Akt/mTOR signaling pathway. literature abstract metadata
- T2 A high-quality chromosome-level genome assembly of apple of Peru (Nicandra physalodes). literature abstract metadata