Black Cumin
Nigella sativa
Nigella sativa, commonly known as black seed or kalonji, originates from regions such as the Mediterranean and Middle East. Traditionally, it has been used in various folk remedies across these areas for conditions like respiratory issues, digestive problems, and skin disorders, though specific recorded uses are not widely documented. Scientific evidence suggests that Nigella sativa may have potential health benefits, including a reduced risk of phlebitis in some studies. Additionally, thymoquinone, a compound found in Nigella sativa, has shown promising results in experimental models for its antioxidant, anti-inflammatory, and neuroprotective properties related to Alzheimer's disease. For cutaneous leishmaniasis, there is limited evidence indicating potential efficacy as an adjunct therapy; however, the current body of research is weakened by methodological limitations. Nigella sativa also demonstrated varying antibacterial activity, with stronger effects on Gram-positive bacteria compared to Gram-negative ones. Safety concerns for Nigella sativa are currently minimal, with no major issues recorded. Similarly, there are no reported drug interactions associated with its use.
- Best evidence
- A
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Phlebitis incidence was lower in the sesame oil and Nigella sativa oil groups compared to the control group.
- Experimental studies suggest thymoquinone from Nigella sativa may have potential antioxidant, anti-inflammatory, and neuroprotective effects in Alzheimer's disease models.
- Nigella sativa showed potential as an adjunct therapy for cutaneous leishmaniasis in some studies, but evidence is limited by methodological weaknesses.
- Black cumin oil showed varying antibacterial activity against tested strains, with stronger effects on Gram-positive bacteria compared to Gram-negative ones.
- Nigella sativa supplementation led to modest reductions in weight, BMI, blood pressure, and fasting blood sugar levels in patients with metabolic diseases.
Frequently asked questions
What is Black Cumin?
Black Cumin (Nigella sativa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Black Cumin?
5 sourced findings are recorded for Black Cumin; the strongest carries evidence grade A. For example: Phlebitis incidence was lower in the sesame oil and Nigella sativa oil groups compared to the control group.
How strong is the evidence for Black Cumin?
The strongest finding for Black Cumin carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Black Cumin safe? What are the side effects?
No major safety issues are recorded for Black Cumin in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Black Cumin interact with medications?
No drug interactions are recorded for Black Cumin in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Black Cumin?
Black Cumin is also known as: чернушка посевная, Nigelle cultivée.
Is Black Cumin a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 The Effect of Nigella sativa Supplementation on Cardiometabolic Health in Patients With Metabolic Diseases: A GRADE-Assessed Systematic Review and Meta-Analysis. literature abstract metadata
- T2 Effect of sesame oil and Nigella sativa oil on the prevention of amiodarone-induced phlebitis: a randomized controlled trial. literature abstract metadata
- T2 Plant-based therapeutics for leishmaniasis: A systematic review emphasizing human studies and clinical trial evidence. literature abstract metadata
- T2 A review on thymoquinone: a promising therapeutic molecule in Alzheimer's. literature abstract metadata
- T2 Antibacterial Activity and Molecular Docking Studies of Black Cumin (Nigella sativa L.) Oil and Its Comparison with Some Antibiotics. literature abstract metadata