Orthosiphon stamineus
Orthosiphon stamineus
Orthosiphon stamineus, commonly known as misai kucing or Java mint, is a traditional plant used primarily in Southeast Asian medicine for urinary excretion and kidney protection. It has also been traditionally employed to help reduce blood pressure. Scientific evidence suggests that Orthosiphon stamineus ethanol extracts and rosmarinic acid may inhibit aldose reductase, which could potentially benefit oxidative stress-related conditions, though the findings are preliminary. Eupatorin from this plant shows potent antioxidant and anti-inflammatory effects, but its chemopreventive roles remain hypothetical. A study indicated that Nuvastatic™, a formulation containing Orthosiphon stamineus, significantly reduced fatigue and improved quality of life in cancer patients compared to placebo, though the results are still limited. The longan-misai kucing combination demonstrated synergistic anti-inflammatory and lipid-clearing effects in models of non-alcoholic fatty liver disease (MAFLD). No major safety issues have been recorded for Orthosiphon stamineus, nor have any significant drug interactions been reported.
- Traditionally for
- urinary excretion · kidney protection
- Traditions
- traditional
- Best evidence
- B
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
Traditional use
- urinary excretion
- kidney protection
- blood pressure reduction
What the science says
- Eupatorin from Orthosiphon stamineus shows potent antioxidant and anti-inflammatory effects but chemopreventive roles remain hypothetical.
- The longan-misai kucing combination showed synergistic anti-inflammatory and lipid-clearing effects, reducing triglycerides, cholesterol, body fat, and adipose tissue weight.
- The study found that Orthosiphon stamineus ethanol extracts and rosmarinic acid showed significant inhibition of aldose reductase, suggesting potential for treating oxidative stress-related conditions.
- The study found that Nuvastatic™ significantly reduced fatigue and improved quality of life in cancer patients compared to placebo, though the findings are preliminary.
Frequently asked questions
What is Orthosiphon stamineus?
Orthosiphon stamineus (Orthosiphon stamineus) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What is Orthosiphon stamineus traditionally used for?
Traditional sources record Orthosiphon stamineus for: urinary excretion, kidney protection, blood pressure reduction. This reflects traditional use, not a proven medical treatment.
Which traditions use Orthosiphon stamineus?
Orthosiphon stamineus appears in these traditions in our sources: traditional.
What does the scientific evidence say about Orthosiphon stamineus?
4 sourced findings are recorded for Orthosiphon stamineus; the strongest carries evidence grade B. For example: Eupatorin from Orthosiphon stamineus shows potent antioxidant and anti-inflammatory effects but chemopreventive roles remain hypothetical.
How strong is the evidence for Orthosiphon stamineus?
The strongest finding for Orthosiphon stamineus carries evidence grade B — moderate evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Orthosiphon stamineus safe? What are the side effects?
No major safety issues are recorded for Orthosiphon stamineus in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Orthosiphon stamineus interact with medications?
No drug interactions are recorded for Orthosiphon stamineus in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Orthosiphon stamineus?
Orthosiphon stamineus is also known as: Почечный чай.
Is Orthosiphon stamineus a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 A phase II randomized, double-blind, placebo-controlled study of Nuvastatic (C50SEW505OESA), a standardized rosmarinic acid-rich polymolecular botanical extract formulation to reduce cancer-related fatigue in patients with solid tumors. literature abstract metadata
- T2 Eupatorin: A comprehensive review of its pharmacological activities and underlying molecular mechanisms. literature abstract metadata
- T2 Aldose Reductase Inhibition by Orthosiphon stamineus Extracts and Constituents Suggests Antioxidant Potential. literature abstract metadata
- T2 Protective effects of a herbal combination (Dimocarpus longan and Orthosiphon stamineus) on metabolic-associated fatty liver disease via the ERα-PI3K-AKT pathway. literature abstract metadata
- T3 Orthosiphon stamineus CC BY-SA 4.0