largebract Indian breadroot
Pediomelum cuspidatum
Pediomelum cuspidatum is a plant traditionally used in East Asian herbal medicine. While it has been utilized in various folk remedies, specific traditional uses have not been extensively documented. Scientific evidence suggests that resveratrol from P. cuspidatum may reduce the replication of certain pathogens, showing potential as a treatment. Phytoestrogens found in the plant might inhibit aromatase enzyme activity and CYP19 gene expression, though this effect is not conclusively established across all studies. Additionally, piceatannol, another stilbene compound from P. cuspidatum, selectively inhibits Streptococcus mutans biofilm formation without broadly affecting bacterial growth. Root endophytic fungi Fm and Pi have been observed to increase certain root secondary metabolite concentrations in the plant, with combined treatment showing enhanced effects for some compounds. No major safety issues or recorded drug interactions are associated with Pediomelum cuspidatum at this time.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Resveratrol reduced PHEV replication in both in vitro and in vivo models, showing potential as a treatment.
- Phytoestrogens may inhibit aromatase enzyme activity and CYP19 gene expression in human tissues.
- Piceatannol, a stilbene from Pediomelum cuspidatum, inhibits Streptococcus mutans biofilm formation with selectivity over growth inhibition.
- Root endophytic fungi Fm and Pi increased concentrations of chrysophanol, resveratrol, and physcion in P. cuspidatum, with dual inoculation being more effective for some compounds.
Frequently asked questions
What is largebract Indian breadroot?
largebract Indian breadroot (Pediomelum cuspidatum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about largebract Indian breadroot?
4 sourced findings are recorded for largebract Indian breadroot; the strongest carries evidence grade D. For example: Resveratrol reduced PHEV replication in both in vitro and in vivo models, showing potential as a treatment.
How strong is the evidence for largebract Indian breadroot?
The strongest finding for largebract Indian breadroot carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is largebract Indian breadroot safe? What are the side effects?
No major safety issues are recorded for largebract Indian breadroot in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does largebract Indian breadroot interact with medications?
No drug interactions are recorded for largebract Indian breadroot in our sources. This does not rule them out — check with a pharmacist.
What are the common names of largebract Indian breadroot?
largebract Indian breadroot is also known as: Psoralée cuspidée.
Is largebract Indian breadroot a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Modulation of Aromatase by Phytoestrogens. literature abstract metadata
- T2 Inhibition of Streptococcus mutans Biofilms by the Natural Stilbene Piceatannol Through the Inhibition of Glucosyltransferases. literature abstract metadata
- T2 Root Endophytic Fungi Regulate Changes in Sugar and Medicinal Compositions of Polygonum cuspidatum. literature abstract metadata
- T2 Suppression of porcine hemagglutinating encephalomyelitis virus replication by resveratrol. literature abstract metadata