largebract Indian breadroot
Pediomelum cuspidatum
Pediomelum cuspidatum is a plant traditionally used in East Asian herbal medicine. Although its specific traditional uses are not well-documented, it has been studied for potential medicinal properties. Scientific evidence suggests that resveratrol from P. cuspidatum may have antiviral effects by reducing PHEV replication both in vitro and in vivo. Phytoestrogens found in the plant might also inhibit aromatase enzyme activity and CYP19 gene expression, though this effect is not extensively studied. Additionally, piceatannol from P. cuspidatum has been shown to inhibit Streptococcus mutans biofilm formation, indicating potential oral health benefits. Root endophytic fungi Fm and Pi have been observed to increase the concentrations of chrysophanol, resveratrol, and physcion in P. cuspidatum, with dual inoculation being more effective for some compounds. To date, no major safety issues or drug interactions have been recorded for this plant, but further research is needed to fully understand its potential benefits and risks.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Resveratrol reduced PHEV replication in both in vitro and in vivo models, showing potential as a treatment.
- Phytoestrogens may inhibit aromatase enzyme activity and CYP19 gene expression in human tissues.
- Piceatannol, a stilbene from Pediomelum cuspidatum, inhibits Streptococcus mutans biofilm formation with selectivity over growth inhibition.
- Root endophytic fungi Fm and Pi increased concentrations of chrysophanol, resveratrol, and physcion in P. cuspidatum, with dual inoculation being more effective for some compounds.
Frequently asked questions
What is largebract Indian breadroot?
largebract Indian breadroot (Pediomelum cuspidatum) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about largebract Indian breadroot?
4 sourced findings are recorded for largebract Indian breadroot; the strongest carries evidence grade D. For example: Resveratrol reduced PHEV replication in both in vitro and in vivo models, showing potential as a treatment.
How strong is the evidence for largebract Indian breadroot?
The strongest finding for largebract Indian breadroot carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is largebract Indian breadroot safe? What are the side effects?
No major safety issues are recorded for largebract Indian breadroot in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does largebract Indian breadroot interact with medications?
No drug interactions are recorded for largebract Indian breadroot in our sources. This does not rule them out — check with a pharmacist.
What are the common names of largebract Indian breadroot?
largebract Indian breadroot is also known as: Psoralée cuspidée.
Is largebract Indian breadroot a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Modulation of Aromatase by Phytoestrogens. literature abstract metadata
- T2 Inhibition of Streptococcus mutans Biofilms by the Natural Stilbene Piceatannol Through the Inhibition of Glucosyltransferases. literature abstract metadata
- T2 Root Endophytic Fungi Regulate Changes in Sugar and Medicinal Compositions of Polygonum cuspidatum. literature abstract metadata
- T2 Suppression of porcine hemagglutinating encephalomyelitis virus replication by resveratrol. literature abstract metadata