FolkKB

Clearweed

Peperomia pellucida

Peperomia pellucida is a small herbaceous plant utilized in various traditional medicine systems. It is traditionally applied to address abdominal and chest complaints, including cough, asthma, fever, diarrhea, and sore throat, as well as for its purported depurative and anodyne properties. Scientific studies suggest potential antidepressant-like effects in mice and demonstrate anti-inflammatory activity in aqueous extracts. Some research indicates possible hypoglycemic properties in rats and potential antibacterial activity against certain fish pathogens in vitro, though these findings are limited. No major safety issues or notable drug interactions have been recorded.

At a glance
Traditionally for
abdominal complaints · chest complaints
Traditions
traditional
Best evidence
D
Cautions
—

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

Traditional use

  • abdominal complaints traditional T3 DRDUKE
  • chest complaints traditional T3 DRDUKE
  • cold traditional T3 DRDUKE
  • cough traditional T3 DRDUKE
  • depurative traditional T3 DRDUKE
  • diarrhea traditional T3 DRDUKE
  • fever traditional T3 DRDUKE
  • flu traditional T3 DRDUKE
  • headache traditional T3 DRDUKE
  • sore throat traditional T3 DRDUKE
  • anodyne traditional T3 DRDUKE
  • asthma traditional T3 DRDUKE
  • bacterial infections traditional T3 DRDUKE
  • boils traditional T3 DRDUKE
  • pectoral traditional T3 DRDUKE

What the science says

  • The ethanol extract of Peperomia pellucida showed some antidepressant-like effects, increasing sucrose preference and reducing oxidative stress parameters in mice. D PMID
  • The aqueous extract of Peperomia pellucida showed stronger anti-inflammatory activity than the methanolic extract in membrane stabilization assays. D PMID
  • EEPP showed hypoglycemic properties reducing 14.7-35.8% of blood glucose levels in rats, though not statistically significant. D PMID
  • Peperomia pellucida exhibited potential antibacterial activity against tested fish pathogens in vitro. D PMID

Frequently asked questions

What is Clearweed?

Clearweed (Peperomia pellucida) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What is Clearweed traditionally used for?

Traditional sources record Clearweed for: abdominal complaints, chest complaints, cold, cough, depurative, diarrhea. This reflects traditional use, not a proven medical treatment.

Which traditions use Clearweed?

Clearweed appears in these traditions in our sources: traditional.

What does the scientific evidence say about Clearweed?

4 sourced findings are recorded for Clearweed; the strongest carries evidence grade D. For example: The ethanol extract of Peperomia pellucida showed some antidepressant-like effects, increasing sucrose preference and reducing oxidative stress parameters in mice.

How strong is the evidence for Clearweed?

The strongest finding for Clearweed carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Clearweed safe? What are the side effects?

No major safety issues are recorded for Clearweed in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Clearweed interact with medications?

No drug interactions are recorded for Clearweed in our sources. This does not rule them out — check with a pharmacist.

What are the common names of Clearweed?

Clearweed is also known as: Herbe couresse.

Is Clearweed a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T3 Dr. Duke's Ethnobotanical Database public domain (USDA ARS — attribute Dr. Duke's)
  2. T2 Antibacterial Activity, Phytochemical Composition, and Cytotoxicity Evaluation of Select Medicinal Plants from Bangladesh. literature abstract metadata
  3. T2 Formulation and in vitro evaluation of an anti-inflammatory herbal suppository containing Peperomia pellucida. literature abstract metadata
  4. T2 Nutritional and Phytochemical Compositions of Peperomia pellucida (L). Kunth from Bogor, West Java, Indonesia, and Its Hypoglycemic Effects in Normoglycemic Sprague-Dawley Rats Subjected to an Acute Glucose Load. literature abstract metadata
  5. T2 Antidepressant-like effect of Peperomia pellucida (L.) Kunth extract: analysis of behavioral and oxidative stress parameters in mice exposed to chronic unpredictable mild stress. literature abstract metadata

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