Clearweed
Peperomia pellucida
Peperomia pellucida, a plant native to Central and South America, has not been traditionally used for any specific medicinal purposes. Scientific studies have shown some potential benefits, including antidepressant-like effects from its ethanol extract, which increased sucrose preference and reduced oxidative stress in mice. The aqueous extract demonstrated stronger anti-inflammatory activity than the methanolic extract, while an ethanol extract also exhibited antibacterial properties against fish pathogens. Regarding hypoglycemic effects, a reduction of 14.7-35.8% in blood glucose levels was observed in rats, though these results were not statistically significant. No major safety concerns or recorded drug interactions have been identified for this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The ethanol extract of Peperomia pellucida showed some antidepressant-like effects, increasing sucrose preference and reducing oxidative stress parameters in mice.
- The aqueous extract of Peperomia pellucida showed stronger anti-inflammatory activity than the methanolic extract in membrane stabilization assays.
- EEPP showed hypoglycemic properties reducing 14.7-35.8% of blood glucose levels in rats, though not statistically significant.
- Peperomia pellucida exhibited potential antibacterial activity against tested fish pathogens in vitro.
Frequently asked questions
What is Clearweed?
Clearweed (Peperomia pellucida) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Clearweed?
4 sourced findings are recorded for Clearweed; the strongest carries evidence grade D. For example: The ethanol extract of Peperomia pellucida showed some antidepressant-like effects, increasing sucrose preference and reducing oxidative stress parameters in mice.
How strong is the evidence for Clearweed?
The strongest finding for Clearweed carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Clearweed safe? What are the side effects?
No major safety issues are recorded for Clearweed in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Clearweed interact with medications?
No drug interactions are recorded for Clearweed in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Clearweed?
Clearweed is also known as: Herbe couresse.
Is Clearweed a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Antibacterial Activity, Phytochemical Composition, and Cytotoxicity Evaluation of Select Medicinal Plants from Bangladesh. literature abstract metadata
- T2 Formulation and in vitro evaluation of an anti-inflammatory herbal suppository containing Peperomia pellucida. literature abstract metadata
- T2 Nutritional and Phytochemical Compositions of Peperomia pellucida (L). Kunth from Bogor, West Java, Indonesia, and Its Hypoglycemic Effects in Normoglycemic Sprague-Dawley Rats Subjected to an Acute Glucose Load. literature abstract metadata
- T2 Antidepressant-like effect of Peperomia pellucida (L.) Kunth extract: analysis of behavioral and oxidative stress parameters in mice exposed to chronic unpredictable mild stress. literature abstract metadata