Shady jerusalem sage
Phlomis umbrosa
Phlomis umbrosa, a plant traditionally used with limited documentation, has shown promise in scientific research. Studies indicate that its water extract may alleviate muscle atrophy induced by dexamethasone through protein synthesis and degradation pathways, while also modulating inflammation and fibrosis related to allergic asthma. Additionally, extracts from Phlomis umbrosa have been observed to potentially aid recovery from physical fatigue due to their antioxidant properties. The scientific evidence is preliminary but suggests potential benefits in conditions such as muscle atrophy and allergic asthma. Notably, no significant safety concerns or recorded drug interactions are associated with this plant, though further research is warranted to confirm these findings comprehensively.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Phlomis umbrosa Turcz. water extract alleviated dexamethasone-induced muscle atrophy in mice by regulating protein synthesis and degradation pathways.
- The treatment with EPT significantly attenuated allergic asthma symptoms by modulating IL-33-mediated inflammation and TGF-β/Smad-dependent fibrosis.
- BLB301 alleviated dexamethasone-induced muscle atrophy in mice by modulating oxidative stress and protein turnover pathways.
- EstroG-100 tended to prolong forced swimming time in mice and showed antioxidant effects, potentially aiding recovery from physical fatigue.
Frequently asked questions
What is Shady jerusalem sage?
Shady jerusalem sage (Phlomis umbrosa) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Shady jerusalem sage?
4 sourced findings are recorded for Shady jerusalem sage; the strongest carries evidence grade D. For example: Phlomis umbrosa Turcz. water extract alleviated dexamethasone-induced muscle atrophy in mice by regulating protein synthesis and degradation pathways.
How strong is the evidence for Shady jerusalem sage?
The strongest finding for Shady jerusalem sage carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Shady jerusalem sage safe? What are the side effects?
No major safety issues are recorded for Shady jerusalem sage in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Shady jerusalem sage interact with medications?
No drug interactions are recorded for Shady jerusalem sage in our sources. This does not rule them out — check with a pharmacist.
Is Shady jerusalem sage a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Phlomis umbrosa Turcz. Water Extract Attenuates Dexamethasone-Induced Muscle Atrophy by Regulating PI3K/Akt/mTOR Pathway. literature abstract metadata
- T2 Effects of Standardized Herbal Extract of Cynanchum wilfordii, Phlomis umbrosa, and Angelica gigas (EstroG-100®) on Physical Fatigue and Oxidative Stress in Vivo and in Vitro. literature abstract metadata
- T2 Black Raspberry and Phlomis Umbrosa Turcz. Extract Mixture (BLB301) Alleviates Dexamethasone-Induced Muscle Atrophy by Modulating Oxidative Stress and Protein Turnover Pathways. literature abstract metadata
- T2 Ameliorating Effects of Phlomis umbrosa Turcz. Root in Ovalbumin-Induced Allergic Asthma: Modulation of IL-33-Mediated Inflammation and TGF-β/Smad-Dependent Fibrosis. literature abstract metadata