Flatstem Milkvetch
Phyllolobium chinense
Phyllolobium chinense is a plant traditionally not associated with any specific medicinal use. Scientific evidence suggests that compounds from related plants, such as Astragalus complanatus seeds, exhibit anti-fibrotic effects and inhibit HSCs activation. Additionally, flavonoids from Phyllolobium chinense (PCFF) have been observed to suppress inflammation in macrophages by inhibiting NF-κB/iNOS signaling pathways. While studies on the plant itself are limited, secondary metabolites from Astragalus complanatus seeds showed promise in enhancing cell viability and inhibiting ferroptosis in HT22 cells. The carbon stock and emissions of Phyllolobium chinense's aboveground biomass have been studied but do not pertain to medicinal use. No significant safety concerns or known drug interactions with Phyllolobium chinense have been recorded, though further research is warranted for a comprehensive understanding.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- The aboveground biomass, carbon stock, and carbon dioxide equivalent emissions varied significantly among different agroforestry tree species and grasses.
- (+)-pinoresinol and desoxyrhapontigenin from Astragalus complanatus seeds dose-dependently enhanced cell viability by regulating the System Xc--GSH-GPX4 axis in ferroptosis-stimulated cells.
- ACSP-I, a polysaccharide from Astragalus complanatus seeds, showed potent anti-fibrotic effects by suppressing hepatic stellate cells activation.
- Phyllolobium chinense Fisch flavonoids (PCFF) suppressed LPS-induced inflammation in macrophages by inhibiting NO production and NF-κB/iNOS signaling.
- MHJJ mitigates CTX-induced alopecia in mice through DNA hypomethylation-mediated activation of the Wnt signaling pathway.
Frequently asked questions
What is Flatstem Milkvetch?
Flatstem Milkvetch (Phyllolobium chinense) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Flatstem Milkvetch?
5 sourced findings are recorded for Flatstem Milkvetch; the strongest carries evidence grade D. For example: The aboveground biomass, carbon stock, and carbon dioxide equivalent emissions varied significantly among different agroforestry tree species and grasses.
How strong is the evidence for Flatstem Milkvetch?
The strongest finding for Flatstem Milkvetch carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Flatstem Milkvetch safe? What are the side effects?
No major safety issues are recorded for Flatstem Milkvetch in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Flatstem Milkvetch interact with medications?
No drug interactions are recorded for Flatstem Milkvetch in our sources. This does not rule them out — check with a pharmacist.
Is Flatstem Milkvetch a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Adoption of novel climate-smart farming systems for enhanced carbon stock and carbon dioxide equivalent emission reduction in cattle corridor areas of Uganda literature abstract metadata
- T2 Structural characterization and anti-hepatic fibrosis effects of a novel polysaccharide from Astragalus complanatus seeds literature abstract metadata
- T2 Phyllolobium chinense Fisch Flavonoids (PCFF) Suppresses the M1 Polarization of LPS-Stimulated RAW264.7 Macrophages by Inhibiting NF-κB/iNOS Signaling Pathway. literature abstract metadata
- T2 Modified Huanjingjian Prevents Chemotherapy-Induced Alopecia by Inhibiting Genomic DNA Methylation of the Wnt Signaling Pathway in Mice. literature abstract metadata
- T2 Discovery of Lignans and Stilbenes from the Seeds of Astragalus complanatus in Ferroptosis Regulation via Directly Acting on SLC7A11/GPX4 Pathway. literature abstract metadata