Picria fel-terrae
Picria fel-terrae
Picria fel-terrae, also known as "earth pepper," is a plant traditionally used in Chinese medicine. It has not been documented to have specific traditional uses outside of its application in Chinese herbal remedies. Scientific evidence suggests potential benefits, with a meta-analysis indicating a significant reduction in plasma glucose levels in diabetic rats treated with Poguntano extract; however, the sample size was limited to only two studies. Eleven saponins were isolated from Picria fel-terrae, some showing hepatoprotective effects, and cucurbitacins Cucurbitacin D, Cucurbitacin F, and Cucurbitacin I were identified as potential inhibitors of STAT3 function. Three new cucurbitane-type triterpene saponins were also isolated but no biological activities have been reported for these compounds. No major safety issues or drug interactions have been recorded to date.
- Best evidence
- A
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Eleven saponins were isolated from Picria fel-terrae, with some showing hepatoprotective effects.
- The study identified cucurbitacins Cucurbitacin D, Cucurbitacin F, and Cucurbitacin I from Picria fel-terrae as potential inhibitors of STAT3 function.
- A significant reduction in plasma glucose levels was observed in diabetic rats treated with Poguntano extract compared to controls, though only two studies were included.
- Three new cucurbitane-type triterpene saponins were isolated from Picria fel-terrae but no biological activities were reported.
Frequently asked questions
What is Picria fel-terrae?
Picria fel-terrae (Picria fel-terrae) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Picria fel-terrae?
4 sourced findings are recorded for Picria fel-terrae; the strongest carries evidence grade A. For example: Eleven saponins were isolated from Picria fel-terrae, with some showing hepatoprotective effects.
How strong is the evidence for Picria fel-terrae?
The strongest finding for Picria fel-terrae carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Picria fel-terrae safe? What are the side effects?
No major safety issues are recorded for Picria fel-terrae in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Picria fel-terrae interact with medications?
No drug interactions are recorded for Picria fel-terrae in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Picria fel-terrae?
Picria fel-terrae is also known as: Picria felterrae.
Is Picria fel-terrae a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Exploring the Potential of Poguntano Extract on Diabetes Management: Systematic Review and Meta-Analysis. literature abstract metadata
- T2 Gene signature-guided isolation identifies cucurbitacins as STAT3 inhibitors from Picria fel-terrae Lour. literature abstract metadata
- T2 Eleven undescribed cucurbitane-type triterpene saponins isolated from the whole plant of Picria fel-terrae Lour. literature abstract metadata
- T2 Three new compounds from the whole herb of Picria fel-terrae. literature abstract metadata