Picria fel-terrae
Picria fel-terrae
Picria fel-terrae, also known as Chinese goldthread or Huanglian, originates from traditional medicine practices in East Asia. Traditionally, it has not been extensively documented for specific uses; however, its active compounds have shown promise in various studies. Scientific evidence suggests a potential benefit in managing diabetes, with one study indicating a reduction in plasma glucose levels in diabetic rats treated with Poguntano extract, though the results are based on limited data and require further validation. Additionally, eleven saponins isolated from Picria fel-terrae have shown hepatoprotective effects, while some cucurbitacins were identified as potential inhibitors of STAT3 function, but no reported biological activities for three new triterpene saponins. Safety concerns are currently minimal, with no major issues recorded; however, the lack of extensive clinical trials means that more research is needed to fully understand its safety profile and potential interactions. As of now, there are no known drug interactions associated with Picria fel-terrae.
- Best evidence
- A
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Eleven saponins were isolated from Picria fel-terrae, with some showing hepatoprotective effects.
- The study identified cucurbitacins Cucurbitacin D, Cucurbitacin F, and Cucurbitacin I from Picria fel-terrae as potential inhibitors of STAT3 function.
- A significant reduction in plasma glucose levels was observed in diabetic rats treated with Poguntano extract compared to controls, though only two studies were included.
- Three new cucurbitane-type triterpene saponins were isolated from Picria fel-terrae but no biological activities were reported.
Frequently asked questions
What is Picria fel-terrae?
Picria fel-terrae (Picria fel-terrae) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Picria fel-terrae?
4 sourced findings are recorded for Picria fel-terrae; the strongest carries evidence grade A. For example: Eleven saponins were isolated from Picria fel-terrae, with some showing hepatoprotective effects.
How strong is the evidence for Picria fel-terrae?
The strongest finding for Picria fel-terrae carries evidence grade A — strong evidence. Grades run A (strongest) to D (preliminary or traditional).
Is Picria fel-terrae safe? What are the side effects?
No major safety issues are recorded for Picria fel-terrae in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Picria fel-terrae interact with medications?
No drug interactions are recorded for Picria fel-terrae in our sources. This does not rule them out — check with a pharmacist.
What are the common names of Picria fel-terrae?
Picria fel-terrae is also known as: Picria felterrae.
Is Picria fel-terrae a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Exploring the Potential of Poguntano Extract on Diabetes Management: Systematic Review and Meta-Analysis. literature abstract metadata
- T2 Gene signature-guided isolation identifies cucurbitacins as STAT3 inhibitors from Picria fel-terrae Lour. literature abstract metadata
- T2 Eleven undescribed cucurbitane-type triterpene saponins isolated from the whole plant of Picria fel-terrae Lour. literature abstract metadata
- T2 Three new compounds from the whole herb of Picria fel-terrae. literature abstract metadata