Pinellia ternata

Pinellia ternata

Pinellia ternata, also known as Ban Xia in traditional Chinese medicine, is a plant traditionally used in East Asian herbal practices for various conditions. While its specific traditional uses are not extensively documented, it has been studied for its potential therapeutic properties. Scientific evidence suggests that JBX1, a heat-tolerant strain of Pinellia ternata, shows enhanced thermotolerance through metabolic adjustments under heat stress. Additionally, research indicates that leaf shape variation in the plant is regulated by hormones, particularly auxins (IAA), and is associated with differences in gene expression among leaf types. The study also identified potential targets for its anti-lung cancer activity, including FGFR4, CDK2, JAK2, KDR, PAK4, PTK2, and PDGFRA, based on in-silico predictions. Furthermore, key genes involved in the alkaloid synthesis pathway of Pinellia ternata have been identified, providing insights into its biosynthesis mechanism. Safety records for Pinellia ternata show no major issues recorded, and there are currently no reported drug interactions associated with its use.

At a glance
Best evidence
D
Cautions

Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.

What the science says

  • JBX1, a heat-tolerant Pinellia ternata germplasm, exhibits enhanced basal thermotolerance through coordinated metabolic adjustments and dynamic reprogramming under heat stress. D PMID
  • The study identified potential targets such as FGFR4, CDK2, JAK2, KDR, PAK4, PTK2, and PDGFRA for Pinellia ternata's anti-lung cancer activity through in-silico methods. D PMID
  • The study found that leaf shape variation in Pinellia ternata is regulated by hormones, particularly IAA, and associated with gene expression differences among leaf types. D PMID
  • The study identified key genes involved in alkaloid synthesis in Pinellia ternata, providing insights into its alkaloid biosynthesis pathway. D PMID

Frequently asked questions

What is Pinellia ternata?

Pinellia ternata (Pinellia ternata) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.

What does the scientific evidence say about Pinellia ternata?

4 sourced findings are recorded for Pinellia ternata; the strongest carries evidence grade D. For example: JBX1, a heat-tolerant Pinellia ternata germplasm, exhibits enhanced basal thermotolerance through coordinated metabolic adjustments and dynamic reprogramming under heat stress.

How strong is the evidence for Pinellia ternata?

The strongest finding for Pinellia ternata carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).

Is Pinellia ternata safe? What are the side effects?

No major safety issues are recorded for Pinellia ternata in our sources, but the data may be incomplete. Consult a qualified professional before use.

Does Pinellia ternata interact with medications?

No drug interactions are recorded for Pinellia ternata in our sources. This does not rule them out — check with a pharmacist.

Is Pinellia ternata a proven treatment?

No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.

Sources

  1. T2 Identification and functional verification of key genes involved in alkaloid biosynthesis in Pinellia ternata. literature abstract metadata
  2. T2 In-silico prediction of multi‑target mechanisms of Pinellia ternata phytochemicals in lung cancer: Evidence from a graph‑attention‑guided virtual screening and multi‑scale simulations. literature abstract metadata
  3. T2 Phytohormone and transcriptome analyses unravel the molecular mechanisms of heterophylly in Pinellia ternata. literature abstract metadata
  4. T2 Integrated Metabolomic and Transcriptomic Analyses Reveal the Differential Molecular Mechanisms Underlying Heat Stress Responses in Two Pinellia ternata Germplasms. literature abstract metadata