Pluchea indica
Pluchea indica
Pluchea indica is a plant traditionally used in Ayurvedic and folk medicine practices. While its specific traditional uses are not well-documented, it has shown potential in various scientific studies. Research indicates that stigmasterol from Pluchea indica leaves may have effects on spermatogenesis, reducing sperm count and increasing morphological abnormalities at 0.75 mg/kg body weight in male rats. Additionally, leaf extracts biosynthesized silver-titanium dioxide nanoparticles demonstrated promising activities including anticancer, antimicrobial, and antioxidant properties. The MgO-ZnO nanocomposite synthesized using Pluchea indica leaf extract also exhibited potential as an antioxidant, antibacterial, and anticancer agent with IC50 values ranging from 31.25 to 179.13 µg/mL. Furthermore, the leaf extracts showed insecticidal activity against Alphitobius diaperinus, though not as effective as Evodia suaveolens. No major safety issues or drug interactions have been recorded for this plant.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Stigmasterol from Pluchea indica leaves significantly reduced spermatogenic cell counts and increased sperm morphological abnormalities in male rats at 0.75 mg/kg BW.
- The MgO-ZnO nanocomposite synthesized using Pluchea indica leaf extract showed potential as an antioxidant, antibacterial, and anticancer agent with IC50 values ranging from 31.25 to 179.13 µg/mL.
- Pluchea indica leaf extract biosynthesized silver-titanium dioxide nanoparticles showed potential anticancer, antimicrobial, and antioxidant activities.
- The leaf extracts of Pluchea indica showed insecticidal activity against Alphitobius diaperinus, but not as effective as Evodia suaveolens.
- The leaf extract of Pluchea indica significantly inhibited cell proliferation in TGF-β-induced prostate stromal cells by arresting the cell cycle at the G0/G1 phase.
Frequently asked questions
What is Pluchea indica?
Pluchea indica (Pluchea indica) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Pluchea indica?
5 sourced findings are recorded for Pluchea indica; the strongest carries evidence grade D. For example: Stigmasterol from Pluchea indica leaves significantly reduced spermatogenic cell counts and increased sperm morphological abnormalities in male rats at 0.75 mg/kg BW.
How strong is the evidence for Pluchea indica?
The strongest finding for Pluchea indica carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Pluchea indica safe? What are the side effects?
No major safety issues are recorded for Pluchea indica in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Pluchea indica interact with medications?
No drug interactions are recorded for Pluchea indica in our sources. This does not rule them out — check with a pharmacist.
Is Pluchea indica a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Standardized Pluchea Indica Leaf Extract Exhibited Antiproliferative Activity Against TGF-β-induced Prostate Stromal Cells (WPMY-1) Through G 1 Phase Cell Cycle Arrest via SMAD2/3 and ERK1/2 Signaling Pathways. literature abstract metadata
- T2 Synthesis of novel MgO-ZnO nanocomposite using Pluchea indica leaf extract and study of their biological activities. literature abstract metadata
- T2 Insecticidal Effects of Extracts from Three Herbal Plants on the Poultry Pest Alphitobius diaperinus. literature abstract metadata
- T2 Green biosynthesis of bimetallic silver titanium dioxide nanoparticles using Pluchea indica with their anticancer, antimicrobial, and antioxidant activities. literature abstract metadata
- T2 Stigmasterol from Pluchea indica Leaves Reduces Spermatogenesis and Alters Sperm Morphology in Male Rat: In Vivo and In Silico Study. literature abstract metadata