Pouzolzia pentandra
Pouzolzia pentandra
Pouzolzia pentandra is a plant traditionally used in few documented practices, with its medicinal applications not extensively explored. Scientific research has shown promising results, particularly with nine methanolic extracts demonstrating potent antiproliferative activity against liver cancer cells, though the strength of evidence varies among different compounds and their isolates such as Stemona collinsae, Gloriosa superba, and emodin. Extracts from Pouzolzia pentandra have also been found to inhibit Helicobacter pylori growth alongside other spice and food plants. Additionally, a compound isolated from the plant exhibited significant anti-inflammatory activity by inhibiting nitric oxide production and pro-inflammatory cytokine release in macrophages. The water methanol fraction of Balanophora abbreviate showed antibacterial activity at 250 microg/ml, though this is not directly related to Pouzolzia pentandra. Safety concerns are currently minimal with no major issues recorded, and there have been no reported drug interactions as of the current research findings.
- Best evidence
- D
- Cautions
- —
Informational only. Traditional use does not mean proven effectiveness. Evidence and safety vary — check the cited sources.
What the science says
- Nine methanolic extracts showed potent antiproliferative activity against liver cancer cells, with Stemona collinsae, Gloriosa superba, and emodin from Ventilago denticulata being notable.
- Extracts from several spice and food plants, including Pouzolzia pentandra, inhibited the growth of Helicobacter pylori strains.
- The water methanol fraction of Balanophora abbreviate showed antibacterial activity at 250 microg/ml.
- Compound 14 from Pouzolzia pentandra showed potent inhibitory activity on nitric oxide production and pro-inflammatory cytokine release in macrophages.
Frequently asked questions
What is Pouzolzia pentandra?
Pouzolzia pentandra (Pouzolzia pentandra) is a plant documented in FolkKB's traditional-medicine reference, drawn from sourced literature and cross-checked against the evidence.
What does the scientific evidence say about Pouzolzia pentandra?
4 sourced findings are recorded for Pouzolzia pentandra; the strongest carries evidence grade D. For example: Nine methanolic extracts showed potent antiproliferative activity against liver cancer cells, with Stemona collinsae, Gloriosa superba, and emodin from Ventilago denticulata being notable.
How strong is the evidence for Pouzolzia pentandra?
The strongest finding for Pouzolzia pentandra carries evidence grade D — preliminary or traditional. Grades run A (strongest) to D (preliminary or traditional).
Is Pouzolzia pentandra safe? What are the side effects?
No major safety issues are recorded for Pouzolzia pentandra in our sources, but the data may be incomplete. Consult a qualified professional before use.
Does Pouzolzia pentandra interact with medications?
No drug interactions are recorded for Pouzolzia pentandra in our sources. This does not rule them out — check with a pharmacist.
Is Pouzolzia pentandra a proven treatment?
No. FolkKB is informational only. Traditional use and early findings are not proof of efficacy or safety — consult a qualified professional and never self-treat.
Sources
- T2 Extracts of spice and food plants from Thai traditional medicine inhibit the growth of the human carcinogen Helicobacter pylori. literature abstract metadata
- T2 Antibacterial activities of four Thai medicinal plants. literature abstract metadata
- T2 Potent Antiproliferative Effect on Liver Cancer of Medicinal Plants Selected from the Thai/Lanna Medicinal Plant Recipe Database "MANOSROI III". literature abstract metadata
- T2 From Plant to Target: Uncovering a Novel Anti-Inflammatory Compound in Pouzolzia pentandra via Phytochemical, Cellular, and Computational Studies. literature abstract metadata